Females expressing Hsap\MYCScer\UAS.2 under the control of Scer\GAL4dm-PG45 show heat sensitive lethality, with reduced survival at 22 and 26[o]C.
Clones in the wing disc expressing Hsap\MYCScer\UAS.2 under the control of Scer\GAL4Act5C.PP show a slight increase in cell size and a slight reduction in the fraction of cells in G[[1]] with a concomitant increase in cells in S or G[[2]] phase compared to controls. The clones show high levels of apoptosis.
Scer\GAL4Myc-PG45/Hsap\MYCUAS.2 is a suppressor | partially of lethal phenotype of MycPG45
Scer\GAL4Myc-PG45/Hsap\MYCUAS.2 is a suppressor | cell autonomous | somatic clone of decreased cell growth rate | somatic clone phenotype of MycPG45
Expression of Hsap\MYCScer\UAS.2 under the control of Scer\GAL4dm-PG45 partially rescues the lethality of dmPG45 males. Surviving adult males have normal bristles, but are sterile. The size of the wings and of the wing cells is almost normal.
The reduced size of homozygous dmPG45 clones in the imaginal disc is completely suppressed if the clones are expressing Hsap\MYCScer\UAS.2 under the control of Scer\GAL4dm-PG45.