FB2024_03 , released June 25, 2024
Allele: Dmel\fussUAS.B
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General Information
Symbol
Dmel\fussUAS.B
Species
D. melanogaster
Name
FlyBase ID
FBal0280474
Feature type
allele
Associated gene
Dmel\fuss
Associated Insertion(s)
Carried in Construct
P{UAS-fuss.B}
Also Known As
UAS-fussB
Key Links
Transgenic product class
cDNA
(Fischer et al., 2012)
wild_type
(Fischer et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Fischer et al., 2012)
wild_type
(Fischer et al., 2012)
Mutagen
in vitro construct
(Fischer et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-fuss.B}
Cytology
Description

UAS drives expression of a fuss cDNA corresponding to fuss-RB.

(Fischer et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
fuss
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of fussScer\UAS.B with Scer\GAL4A9 causes lethality of males at the late pupal stage, while the few female escapers show a strong disruption in wing development: wings are smaller (27% compared to controls), lacks veins, and are poorly unfolded.

      (Fischer et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4fuss-MI13731-GAL4/fussUAS.B rescues fussdelDS/fussdelDS.MI13731-GAL4

      (Rass et al., 2019)
      Comments

      Expressing fussUAS.B under the control of Scer\GAL4fuss-MI13731-GAL4 (the intrinsic Gal4 driver of fussdelDS.MI13731-GAL4) rescues the bitter sensing impairment of fussdelDS/fussdelDS.MI13731-GAL4 adults.

      (Rass et al., 2019)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      fussScer\UAS.B
      fussUAS.B
      Name Synonyms
      Secondary FlyBase IDs
        References (2)