Spermatogenesis in S-Lap1Δ7 homozygotes shows normal cell divisions, normal nebenkern number and formation, normal length of elongated cysts, normal establishment of individualization complexes around the needle shaped nuclei, and normal number of total individualization complexes; however, individualization complexes migrate less frequently, but synchronously, as compared to controls. As in controls, elongated spermatids shows normal axoneme structures, there is complete formation of the two mitochondrial derivatives, and paracrystalline material start accumulating in the major mitochondrial derivative, although the major mitochondrial derivative has abnormal size and the paracrystalline material is disorganized/dispersed.
loopin-1MI06848 has male sterile | recessive phenotype, non-suppressible by S-Lap1int.Tag:HA
loopin-1[+]/loopin-1MI06848 is a non-enhancer of male semi-sterile | dominant phenotype of S-Lap1Δ7
loopin-1[+]/loopin-1MI06848 is a non-suppressor of male semi-sterile | dominant phenotype of S-Lap1Δ7
S-Lap2MI14597, loopin-1[+]/loopin-1MI06848 has male semi-sterile | dominant phenotype
S-Lap3MB01319, loopin-1[+]/loopin-1MI06848 has male semi-sterile | dominant phenotype
S-Lap5Δ14, loopin-1[+]/loopin-1MI06848 has semi-sterile | dominant phenotype
loopin-1MI06848/+, S-Lap4MB11296/+ males yield fewer offspring than controls.
loopin-1MI06848 is rescued by loopin-1+tLa