Spermatogenesis in S-Lap1Δ7 homozygotes shows normal cell divisions, normal nebenkern number and formation, normal length of elongated cysts, normal establishment of individualization complexes around the needle shaped nuclei, normal frequency occurrence of individualization complex migration; however, individualization complex migration can be asynchronous and the associated major mitochondrial derivatives show structural defects (investment cones are dispersed but DJ-GFP distribution is slightly dashed). As in controls, elongated spermatids shows normal axoneme structures, there is complete formation of the two mitochondrial derivatives, and paracrystalline material start accumulating in the major mitochondrial derivative, although the major mitochondrial derivative has abnormal size and the paracrystalline material is disorganized/dispersed.
S-Lap2MI14597 has male sterile | recessive phenotype, non-suppressible by S-Lap1+tLa
S-Lap2MI14597 has male sterile | recessive phenotype, non-suppressible by S-Lap1int.Tag:HA
S-Lap2[+]/S-Lap2MI14597 is an enhancer of male semi-sterile | dominant phenotype of S-Lap1Δ7
S-Lap1Δ7, S-Lap2[+]/S-Lap2MI14597 has male semi-sterile | dominant phenotype
S-Lap1Δ7/S-Lap1[+], S-Lap2MI14597 has male sterile | dominant phenotype
S-Lap2MI14597, loopin-1[+]/loopin-1MI06848 has male semi-sterile | dominant phenotype
S-Lap2MI14597/+, S-Lap3MB01319/+ males, S-Lap2MI14597/+, S-Lap4MB11296/+ males and S-Lap2MI14597/+, S-Lap5Δ14/+ males yield fewer offspring than controls.