FlyBase Allele Report: Dmel\mys[NIG.1560R]

General Information

Symbol

Dmel\mys^NIG.1560R

Species

D. melanogaster

Name

FlyBase ID

FBal0272267

Feature type

allele

Associated gene

Dmel\mys

Associated Insertion(s)

Carried in Construct

P{NIG.1560R}

Also Known As

1560R

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

(Japanese National Institute of Genetics, 2012.5.21)

Progenitor genotype

Carried in construct

P{NIG.1560R}

Cytology

Description

UASt regulatory sequences drive expression of a 500bp inverted repeat.

(Japanese National Institute of Genetics, 2012.5.21)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-1560R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell shape | third instar larval stage, with Scer\GAL4^pnr-MD237

(Wang et al., 2015)

decreased size, with Scer\GAL4^sr-md710

(Tiwari et al., 2015)

increased cell size | third instar larval stage, with Scer\GAL4^pnr-MD237

(Wang et al., 2015)

lethal - all die during embryonic stage, with Scer\GAL4^sr-md710

(Tiwari et al., 2015)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of mys^GD15002 RNAi under the control of Scer\GAL4^pnr-MD237 results in abnormal large syncitia being formed in third instar larval epidermis as well as detachment of muscle fibers from tendon cells.

(Wang et al., 2015)

Expression of mys^NIG.1560R under the control of Scer\GAL4^slbo.2.6 results in a delay in border follicle cell migration.

(Kókai et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^slbo.2.6, mys^NIG.1560R has border follicle cell phenotype, enhanceable by CalpB⁵⁰⁵

(Kókai et al., 2012)

Enhancer of

Statement

Reference

mys^NIG.1560R/Scer\GAL4^slbo.2.6 is an enhancer of border follicle cell phenotype of CalpB⁵⁰⁵

(Kókai et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Females expressing mys^NIG.1560R under the control of Scer\GAL4^slbo.2.6 in a CalpB⁵⁰⁵ background show an increase in the severity of the border follicle cell migration defect compared to either CalpB⁵⁰⁵ single mutants or females expressing mys^NIG.1560R under the control of Scer\GAL4^slbo.2.6 in a wild-type background.

(Kókai et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

mys^NIG.1560R

mysⁱ

(Sun et al., 2021)

β-Integrin^RNAi#2

(Wang et al., 2015)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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