FB2024_03 , released June 25, 2024
Allele: Dmel\RN-treUAS.cHa
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General Information
Symbol
Dmel\RN-treUAS.cHa
Species
D. melanogaster
Name
FlyBase ID
FBal0264416
Feature type
allele
Associated gene
Dmel\RN-tre
Associated Insertion(s)
Carried in Construct
P{UAS-RN-tre.H}
Key Links
Transgenic product class
wild_type
(Houalla et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Houalla et al., 2010)
Mutagen
in vitro construct
(Houalla et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-RN-tre.H}
Cytology
Description

UASt regulatory sequences drive expression of full-length RN-tre coding sequences (corresponding to LD38355).

(Houalla et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
RN-tre
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of RN-treScer\UAS.cHa in the developing eye under the control of Scer\GAL4GMR.PF generates a R-cell mis-localization defect.

      Flies expressing RN-treScer\UAS.cHa in the photoreceptor cells of the developing eye under the control of Scer\GAL4GMR.long display a rough eye phenotype.

      (Houalla et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      RN-treUAS.cHa, Scer\GAL4GMR.long has eye phenotype, enhanceable by Rab52/Rab5[+]

      (Houalla et al., 2010)

      RN-treUAS.cHa, Scer\GAL4GMR.long has eye phenotype, enhanceable by Rab11ex2/Rab11[+]

      (Houalla et al., 2010)
      NOT Enhanced by
      Statement
      Reference

      RN-treUAS.cHa, Scer\GAL4GMR.long has eye phenotype, non-enhanceable by Rab6[+]/Rab6D23E

      (Houalla et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Reducing the dosage of Rab5 through a Rab52 heterozygous background significantly enhances the RN-treScer\UAS.cHa-induced rough eye phenotype.

      Reducing the dosage of Rab11 through a Rab11ex2 heterozygous background significantly enhances the RN-treScer\UAS.cHa-induced rough eye phenotype.

      Reducing the dosage of Rab6 through a Rab6D23E heterozygous background does not affect the RN-treScer\UAS.cHa-induced rough eye phenotype.

      (Houalla et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      RN-treScer\UAS.cHa
      RN-treUAS.cHa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)