FB2024_03 , released June 25, 2024
Allele: Dmel\IncenpGL00279
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General Information
Symbol
Dmel\IncenpGL00279
Species
D. melanogaster
Name
FlyBase ID
FBal0262748
Feature type
allele
Associated gene
Dmel\Incenp
Associated Insertion(s)
Carried in Construct
P{TRiP.GL00279}
Also Known As
Incenp RNAi, GL00279
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2011.7.19)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2011.7.19)
Mutagen
in vitro construct
(Ni et al., 2011.7.19)
Progenitor genotype
Carried in construct
P{TRiP.GL00279}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-GL00279
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of IncenpGL00279 under the control of Scer\GAL4VP16.nos.UTR but not Scer\GAL4VP16.mat.αTub67C leads to production of female germline cysts that do not develop past the germarium when compared to controls.

      Expression of IncenpGL00279 under the control Scer\GAL4VP16.mat.αTub67C leads to absence of microtubules surrounding the karyosome and a failure of homologous centromeres to separate (Scer\GAL4[VP16.mat.αTub67C]) in oocytes when compared to controls.

      (Radford et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Suppressor of
      Other
      Statement
      Reference

      Incenp::Mis12INbox.UASp.Tag:FLAG, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has oocyte phenotype

      (Wang et al., 2021)

      IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, borr::IncenpΔC.ΔHP1.UASp.RR has meiotic spindle | oogenesis phenotype

      (Wang et al., 2021)

      IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, borr::IncenpΔC.ΔHP1.UASp.RR has meiotic spindle midzone | oogenesis | absent phenotype

      (Wang et al., 2021)

      IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, borr::IncenpΔC.ΔHP1.UASp.RR has kinetochore microtubule | oogenesis phenotype

      (Wang et al., 2021)

      IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, borr::IncenpΔC.UASp.RR has oocyte phenotype

      (Wang et al., 2021)

      IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, borr::IncenpΔC.UASp.RR has meiotic spindle | oogenesis phenotype

      (Wang et al., 2021)

      IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, borr::IncenpΔC.UASp.RR has meiotic spindle midzone | oogenesis | absent phenotype

      (Wang et al., 2021)

      IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, borr::IncenpΔC.UASp.RR has kinetochore microtubule | oogenesis phenotype

      (Wang et al., 2021)

      IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, borr::IncenpUASp.RR has oocyte phenotype

      (Wang et al., 2021)

      Incenp::Mis12INbox.UASp.Tag:FLAG, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has meiotic spindle | oogenesis phenotype

      (Wang et al., 2021)

      IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, borr::IncenpUASp.RR has meiotic spindle | oogenesis phenotype

      (Wang et al., 2021)

      Det::IncenpUASp.RR, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has meiotic spindle midzone | oogenesis | absent phenotype

      (Wang et al., 2021)

      Incenp::Su(var)205UASp.RR, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has meiotic spindle | oogenesis phenotype

      (Wang et al., 2021)

      Incenp::Su(var)205UASp.RR, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has meiotic spindle midzone | oogenesis | absent phenotype

      (Wang et al., 2021)

      Incenp::Su(var)205UASp.RR, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has kinetochore microtubule | oogenesis phenotype

      (Wang et al., 2021)

      Incenp::Mis12INbox.UASp.Tag:FLAG, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, feo::IncenpINbox.UASp.Tag:MYC has oocyte phenotype

      (Wang et al., 2021)

      Incenp::Mis12INbox.UASp.Tag:FLAG, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has meiotic spindle midzone | oogenesis | absent phenotype

      (Wang et al., 2021)

      Incenp::Mis12INbox.UASp.Tag:FLAG, Incenp::subINbox.UASp.Tag:MYC, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has oocyte phenotype

      (Wang et al., 2021)

      Incenp::Mis12UASp.RR, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has oocyte phenotype

      (Wang et al., 2021)

      Incenp::Mis12UASp.RR, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has meiotic spindle | oogenesis phenotype

      (Wang et al., 2021)

      Incenp::Mis12UASp.RR, IncenpGL00279, Scer\GAL4VP16.mat.αTub67C has meiotic spindle midzone | oogenesis | absent phenotype

      (Wang et al., 2021)

      IncenpGL00279, Scer\GAL4VP16.mat.αTub67C, borr::IncenpΔC.ΔHP1.UASp.RR has oocyte phenotype

      (Wang et al., 2021)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      IncenpGL00279
      Name Synonyms
      Secondary FlyBase IDs
        References (4)