FB2024_03 , released June 25, 2024
Allele: Dmel\ssx55
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General Information
Symbol
Dmel\ssx55
Species
D. melanogaster
Name
FlyBase ID
FBal0261138
Feature type
allele
Associated gene
Dmel\ssx
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Cline et al., 2010)
Progenitor genotype
P{EPgy2}ssxEY14203
(Cline et al., 2010)
Caused by aberration
Df(1)ssx55
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a 3268bp deletion which removes the entire CG14770 gene and part of the ssx gene (breakpoint is in exon 6), eliminating half of the ssx open reading frame (including the two RNA recognition motifs).

(Cline et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous females and hemizygous males show normal viability and fecundity.

      (Cline et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      ssx55/ssx55 is a non-enhancer of partially lethal - majority die | dominant | female phenotype of Sxlf1

      (Cline et al., 2010)
      Suppressor of
      Statement
      Reference

      ssx55 is a suppressor of visible | male phenotype of SxlM12

      (Cline et al., 2010)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      ssx55 is a suppressor of abdominal tergite 5 | male phenotype of SxlM12

      (Cline et al., 2010)

      ssx55 is a suppressor of abdominal tergite 6 | male phenotype of SxlM12

      (Cline et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The weak dominant female-lethal effect of Sxlf1 is not enhanced by ssx55/ssx55.

      Only 16% of ssx55 SxlM12/Y males have etching of one or more abdominal tergites 5 or 6.

      (Cline et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ssx55
      (Cline et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)