FB2024_03 , released June 25, 2024
Allele: Dmel\nanosHMS00785
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General Information
Symbol
Dmel\nanosHMS00785
Species
D. melanogaster
Name
FlyBase ID
FBal0257466
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing nosHMS00785 under the control of Scer\GAL4Mef2.PR leads to a small but significant decrease in adult climbing ability, but does not have an obvious effect in the thorax muscles; muscle mitochondria also do not show obvious defects.

Expressing nosHMS00785 under the control of Scer\GAL4Cg.PA does not seem to lead to mitochondrial defects in the third instar larval fat body (as assessed by MitoGFP).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of either RbfHMS03004 or mip130HMS00462 with nosJF02931 under the control of Scer\GAL4nub.PU (using UAS-Dicer2 to enhance RNAi efficiency) results in adult wing defects (minor ectopic venation). No wing phenotype is observed upon co-expression of either E2f2JF02828 or mip120HMS00461 with nosHMS00785.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
nanosHMS00785
nosHMS00785
Name Synonyms
Secondary FlyBase IDs
    References (5)