FB2024_03 , released June 25, 2024
Allele: Scer\GAL4Gr93a.5
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General Information
Symbol
Scer\GAL4Gr93a.5
Species
S. cerevisiae
Name
FlyBase ID
FBal0249515
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Gr93a-GAL4.5}
Also Known As
Gr93a-GAL4, Gr93a
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Weiss et al., 2011)
Progenitor genotype
Carried in construct
P{Gr93a-GAL4.5}
Cytology
Description

A 5kb Gr93a promoter fragment is fused upstream of sequence encoding a GAL4 driver.

(Weiss et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
Gr93a
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      gustatory receptor neuron of the epiphysis
      (Kwon et al., 2011)
      larval gnathal ganglion
      (Kwon et al., 2011)
      larval gustatory receptor neuron of the epiphysis DP1
      (Apostolopoulou et al., 2016, Choi et al., 2016)
      larval gustatory receptor neuron of the epiphysis DP5
      (Choi et al., 2016)
      adult stage
      gustatory receptor neuron | subset of short labellar taste bristle | subset
      (Weiss et al., 2011)
      high salt/bitter-sensing neuron of adult labellum sensillum
      (Weiss et al., 2011)
      short labellar taste bristle S-a | faint
      (Weiss et al., 2011)
      adult abdominal multidendritic neuron | subset
      (Park and Kwon, 2011)
      short labellar taste bristle S-a
      (Weiss et al., 2011)
      bitter-sensing neuron | subset
      (Israel et al., 2022)
      Additional Information
      Statement
      Reference

      ScerGAL4Gr93a.5 drives expression in the following series of neurons. Larval gustatory receptor neuron of the epiphysis DP1, where it is coexpressed with ScerGAL4Gr33a.4.7, ScerGAL4Gr66a.1.8, ScerGAL4Gr32a.3.7.PW, ScerGAL4Gr22b.5.8, ScerGAL4Gr39a.a.3.4, ScerGAL4Gr39b.4.4, ScerGAL4Gr9a.6.3, ScerGAL4Gr22d.3.1, ScerGAL4Gr22e.2.5, ScerGAL4Gr28b.a.3, ScerGAL4Gr39a.b.1, ScerGAL4Gr58b.1, and ScerGAL4Gr59d.4.1. Larval gustatory receptor neuron of the epiphysis DP5.

      (Choi et al., 2016)

      ScerGAL4Gr93a.5 drives expression in adult abdominal multidendritic neurons with with dorsal processes extending along the left-right axis, as well as in multidendritic neurons with lateral processes extending anteroposteriorly; these major processes have several protruding dendrites. Expression is also observed in projections to the abdominal ganglion.

      (Park and Kwon, 2011)

      ScerGAL4Gr93a.5 is expressed in gustatory neurons of 6 of the bitter-sensitive short labellar taste bristles.

      (Weiss et al., 2011)

      ScerGAL4Gr93a.5 is expressed in some of the short bitter-sensitive sensilla of the labellum.

      (Weiss et al., 2011, Weiss et al., 2011)

      ScerGAL4Gr93a.5 drives expression in one gustatory receptor neuron of the larval dorsal pharyngeal sense organ (DPS or epiphysis).

      (Kwon et al., 2011)
       
      Marker for
      bitter-sensing neuron
      (Israel et al., 2022)
      Reflects expression of
      Gr93a
      (Israel et al., 2022, Apostolopoulou et al., 2016, Kwon et al., 2011, Park and Kwon, 2011, Weiss et al., 2011, Weiss et al., 2011)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ablation of Scer\GAL4Gr93a.5-expressing neurons does not affect sensitivity to the gustatory sex pheromone (S,Z,Z)-CH503: as in wild type, courtship defects are seen in these flies in response to (S,Z,Z)-CH503.

      (Shankar et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Gr47aUAS.cLa/Scer\GAL4Gr93a.5 fails to rescue Gr47a1

      (Lee et al., 2015)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4Gr93a.5
      Name Synonyms
      Secondary FlyBase IDs
        References (13)