FB2024_03 , released June 25, 2024
Allele: Dmel\Doa6d2
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General Information
Symbol
Dmel\Doa6d2
Species
D. melanogaster
Name
FlyBase ID
FBal0248343
Feature type
allele
Associated gene
Dmel\Doa
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ambrus et al., 2009)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Doa6d2 is a suppressor of eye | somatic clone phenotype of E2f1rM729

      (Ambrus et al., 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Doa6d2 can suppress the proliferation block of E2frM729 clones, allowing recovery of double mutant clones in the eye.

      The second mitotic wave is weakly rescued in Doa6d2 E2frM729 double mutant clones in the eye disc, with double mutant cells only being sporadically labelled with BrdU in the second mitotic wave. Those double mutant cells that do incorporate BrdU are always found to be significantly more than adjacent wild-type cells that incorporate BrdU.

      (Ambrus et al., 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Doa01705b

      (Ambrus et al., 2009)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      6d2
      (Ambrus et al., 2009)
      Doa6d2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)