FB2024_03 , released June 25, 2024
Allele: Dmel\wdeTD63
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General Information
Symbol
Dmel\wdeTD63
Species
D. melanogaster
Name
FlyBase ID
FBal0242718
Feature type
allele
Associated gene
Dmel\wde
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Koch et al., 2009)
Mutagen
FLPase
(Koch et al., 2009)
Progenitor genotype
P{XP}d01917
(Koch et al., 2009)
P{XP}d03942
(Koch et al., 2009)
Cytology
Description

Recombination between the two progenitor insertions has resulted in deletion of the intervening sequence, which deletes the entire coding region of wde.

(Koch et al., 2009)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:10,798,906..10,809,018 [-]
Comment:

Deletion of fwde resulting from FLP-catalyzed recombination using the FRT-containing transposons P{XP}d01917 and P{XP}d03942.

(Koch et al., 2009)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Animals homozygous for any of wded06198, wdeEY00884 or wdeTD63 mutant alleles or transheterozygous for any combination of the three alleles die at pupal stages. Rare escapers can be obtained by raising homozygous mutant larvae separated from their heterozygous siblings. Adult homozygous escapers are weak and survive only for a few days. The ovaries of homozygous mutant females are tiny and do not develop to the stage when egg chambers bud off from the germarium.

      Homozygous wdeTD63 mutant germ-line clones do not produce any eggs.

      (Koch et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      wdeTD63 is rescued by wdeUASp.GFP/Scer\GAL4da.G32

      (Koch et al., 2009)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      wdeTD63
      (Sarkar et al., 2023, Koch et al., 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)