Amino acid replacement: M1I.
The amino acid replacement introduced into the SuUR sequences present in the construct removes the starting Met residue. It is possible that translation occurs from Met residues situated at positions 141 and/or 157, as truncated protein(s) are detected when the construct is expressed.
Expression of SuURrs6.Scer\UAS under the control of Scer\GAL4AB1 does not result in the disappearance of weak points in the polytene chromosomes of salivary glands.
Expression of SuURrs6.Scer\UAS under the control of Scer\GAL4AB1 in a SuURES background results in larvae with numerous weak points in intercalary heterochromatin regions (this indicates rescue of the SuURES phenotype of lack of underreplication).