FlyBase Allele Report: Dmel\Mp[ΔC12-25]

General Information

Symbol

Dmel\Mp^ΔC12-25

Species

D. melanogaster

Name

FlyBase ID

FBal0230295

Feature type

allele

Associated gene

Dmel\Mp

Associated Insertion(s)

PBac{PB3.WH3}Mp^ΔC12-25

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

FLPase

Nature of the Allele

Allele class

Mutagen

FLPase

(Meyer and Moussian, 2009)

Progenitor genotype

PBac{PB}c06608a

(Meyer and Moussian, 2009)

PBac{WH}Mp^f03008

(Meyer and Moussian, 2009)

Associated Insertion(s)

PBac{PB3.WH3}Mp^ΔC12-25

Cytology

Description

Recombination between the two progenitor insertions has resulted in a 19.89kb deletion which removes some of the mp locus, including the whole coding sequence for the NC1 domain (exons 12 to 25). A residual insertion remains.

(Meyer and Moussian, 2009)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

3L:7,039,044..7,058,928 [+]

Comment:

Scer\FRT-mediated recombination between the two progenitor insertions has deleted the sequence between them.

(Meyer and Moussian, 2009)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate

(Meyer and Moussian, 2009)

abnormal neuroanatomy | embryonic stage

(Meyer and Moussian, 2009)

viable

(Meyer and Moussian, 2009)

Phenotype Manifest In

larval intersegmental nerve branch ISNb of A1-7

(Meyer and Moussian, 2009)

Detailed Description

Statement

Reference

Homozygous adults eclose several days later than control siblings.

ISNb pathfinding errors are seen in 21.4% of hemisegments in mp^ΔC12-25 embryos.

(Meyer and Moussian, 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Mp^ΔC12-25 is rescued by Scer\GAL4^how-24B/Mp^{ES.UAS.Tag:SS(wg)}

(Meyer and Moussian, 2009)

Mp^ΔC12-25 is rescued by Mp^3hNC1.UAS/Scer\GAL4^how-24B

(Meyer and Moussian, 2009)

Not rescued by

Mp^ΔC12-25 is not rescued by Scer\GAL4^how-24B/Mp^{NC1.UAS.Tag:SS(wg)}

(Meyer and Moussian, 2009)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Mp^ΔC12-25

dmp^ΔC12-25

(Meyer and Moussian, 2009)

mp^ΔC12-25

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close