FB2024_03 , released June 25, 2024
Allele: Dmel\Hip1ΔANTH.UAS
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General Information
Symbol
Dmel\Hip1ΔANTH.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0221213
Feature type
allele
Associated gene
Dmel\Hip1
Associated Insertion(s)
Carried in Construct
P{UAS-Hip1.ΔANTH}
Key Links
Transgenic product class
cDNA
(Moores et al., 2008)
wild_type
(Moores et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Moores et al., 2008)
wild_type
(Moores et al., 2008)
Mutagen
in vitro construct
(Moores et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-Hip1.ΔANTH}
Cytology
Description

UASt regulatory sequences drive expression of the Hip1 LD20514 cDNA.

(Moores et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hip1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      microchaeta & mesothoracic tergum, with Scer\GAL4ap-md544

      (Moores et al., 2008)

      microchaeta & mesothoracic tergum, with Scer\GAL4pnr-MD237

      (Moores et al., 2008)
      Detailed Description
      Statement
      Reference

      Expression of Hip1ΔANTH.Scer\UAS under the control of either Scer\GAL4ap-md544 or Scer\GAL4pnr-MD237 results in an increase in density of microchaetae throughout the dorsal notum. There is no effect on gross bristle morphology or on the number or position of macrochaetae.

      (Moores et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      Scer\GAL4pnr-MD237/Hip1ΔANTH.UAS is a non-enhancer of visible | dominant phenotype of E(spl)m8-HLH1

      (Moores et al., 2008)
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4pnr-MD237/Hip1ΔANTH.UAS is a non-suppressor of visible | dominant phenotype of E(spl)m8-HLH1

      (Moores et al., 2008)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Hip1ΔANTH.UAS, Scer\GAL4pnr-MD237 has microchaeta & mesothoracic tergum phenotype, suppressible by ac4

      (Moores et al., 2008)
      NOT Enhancer of
      Statement
      Reference

      Scer\GAL4pnr-MD237/Hip1ΔANTH.UAS is a non-enhancer of microchaeta & mesothoracic tergum phenotype of E(spl)m8-HLH1

      (Moores et al., 2008)
      Suppressor of
      Statement
      Reference

      Hip1ΔANTH.UAS, Scer\GAL4pnr-MD237 is a suppressor | partially of microchaeta & mesothoracic tergum phenotype of Scer\GAL4pnr-MD237, dxUAS.cMa

      (Moores et al., 2008)

      Scer\GAL4pnr-MD237/Hip1ΔANTH.UAS is a suppressor of microchaeta & mesothoracic tergum phenotype of NMcd1

      (Moores et al., 2008)
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4pnr-MD237/Hip1ΔANTH.UAS is a non-suppressor of microchaeta & mesothoracic tergum phenotype of E(spl)m8-HLH1

      (Moores et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Hip1ΔANTH.Scer\UAS under the control of Scer\GAL4pnr-MD237 suppresses the abnormal microchaetae density phenotype seen on the notum of NMcd1 flies.

      Expression of Hip1ΔANTH.Scer\UAS under the control of Scer\GAL4pnr-MD237 has no effect on the increased density of microchaetae on the notum seen in E(spl)1/+ flies.

      The increased density of microchaetae on the notum caused by expression of Hip1ΔANTH.Scer\UAS under the control of Scer\GAL4pnr-MD237 is suppressed by ac4/+ or ac4/Y.

      The phenotype of reduced microchaetae on the notum which is caused by expression of dxScer\UAS.cMa under the control of Scer\GAL4pnr-MD237 at 19[o]C is partially suppressed by co-expression of Hip1ΔANTH.Scer\UAS; bristle number is increased and the number of abnormal bristles is reduced.

      (Moores et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hip1ΔANTH.Scer\UAS
      Hip1ΔANTH.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)