FB2024_03 , released June 25, 2024
Allele: Dmel\ac4
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General Information
Symbol
Dmel\ac4
Species
D. melanogaster
Name
FlyBase ID
FBal0000164
Feature type
allele
Associated gene
Dmel\ac
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Anterior and posterior dorsocentrals removed; also thoracic hairs. RK2.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      ac[+]/ac4 is an enhancer of eye phenotype of Scer\GAL4GMR.PF, fruNP0021

      (Goto et al., 2011)
      Suppressor of
      Statement
      Reference

      ac4 is a suppressor of microchaeta & mesothoracic tergum phenotype of Hip1UAS.cMa, Scer\GAL4pnr-MD237

      (Moores et al., 2008)

      ac4 is a suppressor of microchaeta & mesothoracic tergum phenotype of Hip1ΔANTH.UAS, Scer\GAL4pnr-MD237

      (Moores et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      An ac4 background enhances the rough eye phenotype found upon expression of fruNP0021 under the control of Scer\GAL4GMR.PF.

      (Goto et al., 2011)

      The increased density of microchaetae on the notum caused by expression of Hip1ΔANTH.Scer\UAS under the control of Scer\GAL4pnr-MD237 is suppressed by ac4/+ or ac4/Y.

      The decreased density of microchaetae on the notum caused by expression of Hip1Scer\UAS.cMa under the control of Scer\GAL4pnr-MD237 is not suppressed by ac4/+ but is suppressed by ac4/Y.

      (Moores et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (1)
      Stocks (1)
      Notes on Origin
      Discoverer

      Dubinin, 1929.

      Induced on: scunspecified.

      Comments
      Comments

      A change also apparently induced in expression of sc, called sc13. The sc component also removes scutellars and often ocellars, postverticals, and first and second orbital bristles.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ac3
      ac4
      (Goto et al., 2011, Christensen et al., 2008.6.11, Moores et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)