UASt regulatory sequences drive expression of an inverted repeat.
Adults expressing lbeGD4157 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4Mef2.PR results in adult/pharate lethality.
Scer\GAL4eve.eme-mediated expression of lbeGD4157 rescues the reduced heart diameter of lbeeve.SS adults, and partially rescues the reduced diastolic and systolic diameters seen in live lbeeve.SS hearts.
Scer\GAL4eve.eme-mediated expression of lbeGD4157 rescues the myofibrillar structure defects of lbeeve.SS adult hearts.