UASt regulatory sequences drive expression of an inverted repeat.
Adults expressing TrlGD8028 under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver show significantly reduced survival on day 6 after a shift to 29[o]C compared to control flies.
Adults expressing TrlGD8028 under the control of Scer\GAL4HCH.Hand show a significant increase in both diastolic and systolic diameters, and a significant decrease in fractional shortening compared to controls. Heart period is not significantly different from controls.
Adults expressing TrlGD8028 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4Mef2.PR results in adult/pharate lethality.
Dcr-2UAS.cDa, Scer\GAL4en-e16E, TrlGD8028 has wing disc | third instar larval stage phenotype
Wing discs co-expressing TrlGD8028 and Dcr-2Scer\UAS.cDa driven by Scer\GAL4en-e16E display large tumors.