UASt regulatory sequences drive expression of an inverted repeat.
Adults expressing SgshGD1578 under the control of Scer\GAL4elav.PLu exhibit progressive climbing defects compared to control and their brains accumulate acidic vesicles (LysoTracker-positive puncta), as compared to controls.
Adults expressing CG14291GD1578 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Scer\GAL4elav.PLu, SgshGD1578 has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by sflGD2336/Scer\GAL4elav.PLu
Scer\GAL4elav.PLu, SgshGD1578 has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by sllGD3032/Scer\GAL4elav.PLu
Scer\GAL4elav.PLu, SgshGD1578 has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by Atg18aGD12342, Scer\GAL4elav.PLu
Scer\GAL4elav.PLu, SgshGD1578 has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by Atg1GD7149, Scer\GAL4elav.PLu
Scer\GAL4elav.PLu, SgshGD1578 has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by Sod1UAS.cAa/Scer\GAL4elav.PLu
Scer\GAL4elav.PLu, SgshGD1578 has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by Sod2UAS.cMa/Scer\GAL4elav.PLu
Scer\GAL4elav.PLu, SgshGD1578 has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by Hsap\HSPA1LUAS.cWa, Scer\GAL4elav.PLu
Scer\GAL4elav.PLu, SgshGD1578 has abnormal locomotor behavior | adult stage | progressive phenotype, non-enhanceable by Rab5UAS.EGFP, Scer\GAL4elav.PLu
Scer\GAL4elav.PLu, SgshGD1578 has abnormal locomotor behavior | adult stage | progressive phenotype, non-enhanceable by Rab5S43N.UAS, Scer\GAL4elav.PLu
Scer\GAL4elav.PLu, SgshGD1578 has abnormal locomotor behavior | adult stage | progressive phenotype, non-enhanceable by BacA\p35UAS.cHa, Scer\GAL4elav.PLu