FB2024_03 , released June 25, 2024
Allele: Dmel\RpL13AEP3614.A
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General Information
Symbol
Dmel\RpL13AEP3614.A
Species
D. melanogaster
Name
FlyBase ID
FBal0194265
Feature type
allele
Associated gene
Dmel\RpL13A
Associated Insertion(s)
P{EP}RpL13AEP3614.A
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Alexander et al., 2006)
Mutagen
Delta2-3 transposase
(Alexander et al., 2006)
Progenitor genotype
Associated Insertion(s)
P{EP}RpL13AEP3614.A
Cytology
Description

The P{EP} element is inserted within the first exon of RpL13A within the protein-coding segment, between the second and third codons.

(Alexander et al., 2006)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      RpL13AEP3614.A heterozygotes show extended developmental time, eclosing 1-2 days later than wild type siblings, and exhibit macrochaetes that are short and slender compared to controls.

      (Alexander et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      RpL13AEP3614.A is an enhancer of visible phenotype of Nnd-1

      (Alexander et al., 2006)

      RpL13AEP3614.A, Scer\GAL4bbg-C96 is an enhancer of visible | adult stage phenotype of Scer\GAL4bbg-C96, mamH.UAS

      (Alexander et al., 2006)
      NOT Enhancer of
      Suppressor of
      Statement
      Reference

      RpL13AEP3614.A, Scer\GAL4309 is a suppressor of visible | adult stage phenotype of Scer\GAL4309, mamH.UAS

      (Alexander et al., 2006)
      NOT Suppressor of
      Statement
      Reference

      RpL13AEP3614.A, Scer\GAL4pnr-MD237 is a non-suppressor of visible | adult stage phenotype of Scer\GAL4pnr-MD237, mamN.UAS

      (Alexander et al., 2006)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      RpL13AEP3614.A is an enhancer of wing margin phenotype of Nnd-1

      (Alexander et al., 2006)

      RpL13AEP3614.A, Scer\GAL4bbg-C96 is an enhancer of wing margin phenotype of Scer\GAL4bbg-C96, mamH.UAS

      (Alexander et al., 2006)
      NOT Enhancer of
      Statement
      Reference

      RpL13AEP3614.A, Scer\GAL4pnr-MD237 is a non-enhancer of mesothoracic tergum & microchaeta phenotype of Scer\GAL4pnr-MD237, mamN.UAS

      (Alexander et al., 2006)
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      RpL13AEP3614.A, Scer\GAL4pnr-MD237 is a non-suppressor of mesothoracic tergum & microchaeta phenotype of Scer\GAL4pnr-MD237, mamN.UAS

      (Alexander et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The wing margin nicking phenotype produced by expression of mamH.Scer\UAS under the control of Scer\GAL4C96 is enhanced in flies heterozygous for RpL13AEP3614.A.

      Wings from male flies hemizygous for Nnd-1 and heterozygous for RpL13AEP3614.A show a severe loss of wing material compared to Nnd-1/Y wings (whereas wings from RpL13AEP3614.A heterozygotes appear wild type).

      The increase in bristle number at the site of the posterior notopleural macrochaete produced by expression of mamH.Scer\UAS under the control of Scer\GAL4309 is slightly suppressed in flies heterozygous for RpL13AEP3614.A as fewer bristles are evident in some cases.

      (Alexander et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EP 3614
      (Alexander et al., 2006)
      RpL13AEP3614.A
      Name Synonyms
      Secondary FlyBase IDs
        References (2)