FB2024_03 , released June 25, 2024
Allele: Dmel\bchs8K
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General Information
Symbol
Dmel\bchs8K
Species
D. melanogaster
Name
FlyBase ID
FBal0193786
Feature type
allele
Associated gene
Dmel\bchs
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Khodosh et al., 2006)
Progenitor genotype
bchsEP2299
(Khodosh et al., 2006)
Cytology
Description

Amino acid replacement: T2656I.

(Khodosh et al., 2006)

Missense mutation in the 'BEACH' domain.

(Khodosh et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:5,918,209..5,918,209 [+]
Nucleotide change:

C5918209T

Amino acid change:

T2656I | bchs-PA

Reported amino acid change:

T2656I

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Khodosh et al., 2006)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      bchs8K mutants show no defects in the larval visual system or embryonic central nervous system.

      (Khodosh et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      bchs8K/bchs[+] is a suppressor | partially of microchaeta phenotype of Rab1193Bi

      (Khodosh et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The microchaeta loss of Rab1193Bi flies is significantly suppressed by bchs8K/+.

      (Khodosh et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      bchs8
      (Khodosh et al., 2006)
      bchs8K
      Name Synonyms
      Secondary FlyBase IDs
        References (1)