Most of the coding region of eyg has been deleted, leaving the C-terminal region (amino acids 292-554).
Unlike overexpression of wild-type eyg, expression of eygC.Scer\UAS, under the control of Scer\GAL4dpp.blk1, does not cause extra ventral eye formation. Expression of eygC.Scer\UAS in a eyg22-2/eygM3-12 background has a dominant-negative effect on the eye and thorax phenotype of these mutants.
Scer\GAL4eyg-22-2/eygC.UAS fails to rescue eyg22-2/eygM3-12
Expression of eygC.Scer\UAS, under the control of Scer\GAL4eyg-22-2, causes a dominant-negative enhancement of the eye and thorax phenotypes of eyg22-2/eygM3-12 mutants.