The RED domain (amino acids 51-102) has been deleted.
Unlike overexpression of wild-type eyg, expression of eygΔRED.Scer\UAS, under the control of Scer\GAL4dpp.blk1, does not cause extra ventral eye formation. Expression of eygΔRED.Scer\UAS in a eyg22-2/eygM3-12 background has a dominant-negative effect on the eye and thorax phenotype of these mutants.
eygΔRED.UAS/Scer\GAL4eyg-22-2 fails to rescue eyg22-2/eygM3-12
Expression of the eygΔRED.Scer\UAS transgene, under the control of Scer\GAL4eyg-22-2, enhances the grooved thorax and reduced eye phenotype of eygM3-12/eyg22-2 mutants.