FB2024_03 , released June 25, 2024
Allele: Dmel\Medadro
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General Information
Symbol
Dmel\Medadro
Species
D. melanogaster
Name
aerodrome
FlyBase ID
FBal0182766
Feature type
allele
Associated gene
Dmel\Med
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Zirin and Mann, 2004)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous clones in the wing result in a non-autonomous reduction of wing size and growth along the proximodistal (PD) axis, which is evident in both the wing blade and hinge. The wing blade clones tend to sort out from the surrounding wild-type cells, forming vesicles. Clones located close to the dorsoventral boundary sometimes induce non-autonomous duplications of wing margin structures. Clones near the anterior-posterior boundary of the wing hinge sometimes show cell autonomous differentiation of lateral hinge elements.

      (Zirin and Mann, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Etymology: the allele is named "aerodrome" after pre-Wright Brothers attempts at heavier-than-air flight.

      (Zirin and Mann, 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Medadro
      Name Synonyms
      aerodrome
      (Zirin and Mann, 2004)
      Secondary FlyBase IDs
        References (1)