FlyBase Allele Report: Scer\GAL4[eve.RN2O]

General Information

Symbol

Scer\GAL4^eve.RN2O

Species

S. cerevisiae

Name

FlyBase ID

FBal0181614

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{RN2O-GAL4}

Also Known As

RN2-O GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Baines, 2003)

Progenitor genotype

Carried in construct

P{RN2O-GAL4}

Cytology

Description

Allele components

Component

Use(s)

Regulatory region(s)

eve

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 16 -- first instar larval stage

larval RP2 motor neuron

(Baines, 2003)

larval DA1 motor neuron

(Baines, 2003)

Additional Information

Statement

Reference

ScerGAL4^eve.RN2O drives expression in aCC and RP2 motor neurons, beginning in early embryonic stage 16, prior to the onset of synptogenesis. This pattern is similar to, but more intense than, that driven by ScerGAL4^eve.RRK.

(Baines, 2003)

Marker for

Reflects expression of

eve

(Baines, 2003)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neurophysiology, with Mmus\Prkaca^mC.UAS

(Baines, 2003)

abnormal neurophysiology, with pum^UAS.cSa

(Mee et al., 2004)

abnormal neurophysiology, with rut^UAS.cZa

(Baines, 2003)

abnormal neurophysiology | first instar larval stage, with tup^{UAS.Tag:Dam,Tag:MYC}

(Wolfram et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^eve.RN2O, tup^{UAS.Tag:Dam,Tag:MYC} has abnormal neurophysiology | first instar larval stage | recessive phenotype, non-enhanceable by Sh¹⁴/Sh¹⁴

(Wolfram et al., 2012)

NOT Enhancer of

Statement

Reference

tup^{UAS.Tag:Dam,Tag:MYC}/Scer\GAL4^eve.RN2O is a non-enhancer of abnormal neurophysiology | first instar larval stage | recessive phenotype of Sh¹⁴

(Wolfram et al., 2012)

Suppressor of

Statement

Reference

Pka-R1^BDK.UAS/Scer\GAL4^eve.RN2O is a suppressor of abnormal neurophysiology | dominant phenotype of Ace^j50

(Baines, 2003)

dnc^UAS.cCa/Scer\GAL4^eve.RN2O is a suppressor of abnormal neurophysiology | dominant phenotype of Ace^j50

(Baines, 2003)

NOT Suppressor of

Statement

Reference

tup^{UAS.Tag:Dam,Tag:MYC}/Scer\GAL4^eve.RN2O is a non-suppressor of abnormal neurophysiology | recessive | first instar larval stage phenotype of Sh¹⁴

(Wolfram et al., 2012)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^eve.RN2O, tup^{UAS.Tag:Dam,Tag:MYC} has embryonic/larval motor neuron | first instar larval stage phenotype, non-enhanceable by Sh¹⁴/Sh¹⁴

(Wolfram et al., 2012)

NOT Enhancer of

Statement

Reference

tup^{UAS.Tag:Dam,Tag:MYC}/Scer\GAL4^eve.RN2O is a non-enhancer of embryonic/larval motor neuron | first instar larval stage phenotype of Sh¹⁴

(Wolfram et al., 2012)

NOT Suppressor of

Statement

Reference

tup^{UAS.Tag:Dam,Tag:MYC}/Scer\GAL4^eve.RN2O is a non-suppressor of embryonic/larval motor neuron | first instar larval stage phenotype of Sh¹⁴

(Wolfram et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

shot^LA.UAS.GFP/Scer\GAL4^eve.RN2O partially rescues shot^unspecified

(Alves-Silva et al., 2012)

Fails to rescue

shot^{RE-ΔCtail.UAS.GFP}/Scer\GAL4^eve.RN2O fails to rescue shot^unspecified

(Alves-Silva et al., 2012)

shot^{RE-3MtLSmut.UAS.GFP}/Scer\GAL4^eve.RN2O fails to rescue shot^unspecified

(Alves-Silva et al., 2012)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^RN2-0

(Wolfram et al., 2012)

Scer\GAL4^eve.RN2O

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close