FlyBase Allele Report: Scer\GAL4[exex-Gal4]

Drives expression in a subset of ventrally projecting motor neurons, some of which persist from larval stages through adulthood to become adult persistent motor neurons.

(FlyBase Curators, 2017)

ScerGAL4^exex-Gal4 drives expression in a subset of larval motor neurons, some of which persist through pupal development to become adult persistent motor neurons.

(Banerjee et al., 2016)

ScerGAL4^exex-Gal4 drives expression in a subset of ventral motor neurons which exit the ventral nerve cord via the ISNb nerve branch. There is co-expression with Oli protein.

(Oyallon et al., 2012)

Marker for

Reflects expression of

exex

(Banerjee et al., 2016, Oyallon et al., 2012)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult motor neuron, with cpx^GD10482

(Banerjee et al., 2021)

adult motor neuron, with para^JF01469

(Banerjee et al., 2021)

adult motor neuron, with Vha100-1^HMJ21907

(Banerjee et al., 2021)

adult motor neuron, with Vha100-1^HMJ21907, Vha100-1^WFI.UAS

(Banerjee et al., 2021)

axon | embryonic stage, with ckn^UAS.cWa

(Weng et al., 2011)

fascicle | embryonic stage, with ckn^UAS.cWa

(Weng et al., 2011)

larval intersegmental nerve branch ISNb of A1-7, with Abl²/Abl^N.UAS.GFP

(O'Donnell and Bashaw, 2013)

larval intersegmental nerve branch ISNb of A1-7 | embryonic stage, with ckn^UAS.cWa

(Weng et al., 2011)

larval longitudinal connective, with robo2^{UAS.Tag:HA,Tag:SS(wg)}

(Evans et al., 2015)

NMJ bouton | adult stage, with cpx^GD10482

(Banerjee et al., 2021)

NMJ bouton | adult stage, with Vha100-1^HMJ21907, Vha100-1^WFI.UAS

(Banerjee et al., 2021)

presynapse | adult stage, with Vha100-1^HMJ21907, Vha100-1^WFI.UAS

(Banerjee et al., 2021)

presynaptic active zone | adult stage, with cpx^GD10482

(Banerjee et al., 2021)

presynaptic active zone | adult stage, with Vha100-1^HMJ21907, Vha100-1^WFI.UAS

(Banerjee et al., 2021)

Detailed Description

Statement

Reference

Activation of Scer\GAL4^exex-Gal4 neurons triggers side-walking behavior; depending on the combination of UAS and light used, different numbers of flies show this behavior: 0% with blue light activating Crei\ChR2^Scer\UAS.cSa, Crei\ChR2^{H134R.Scer\UAS.2A.T:Avic\GFP-EYFP} or Crei\ChR2^{C128T.Scer\UAS.T:Avic\GFP-YFP}; 0% with red or green light activating Crei\ChR1[C1V1.T-T.Scer\UAS. T:Avic \GFP-EYFP]; around 80% with red or green light activating Crei\ChR1^{ReaChR.Scer\UAS.T:Crei\ChR2,T:Avic\GFP-mCitrine}.

(Inagaki et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^exex-Gal4, cpx^GD10482 has abnormal neurophysiology | adult stage phenotype, enhanceable by para^JF01469/Scer\GAL4^exex-Gal4

(Banerjee et al., 2021)

NOT Enhanced by