FB2024_03 , released June 25, 2024
Allele: Dmel\e(y)3ΔPHD
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General Information
Symbol
Dmel\e(y)3ΔPHD
Species
D. melanogaster
Name
FlyBase ID
FBal0180074
Feature type
allele
Associated gene
Dmel\e(y)3
Associated Insertion(s)
Carried in Construct
P{e(y)3ΔPHD}
Key Links
Transgenic product class
inframe_deletion
(Shidlovskii et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Shidlovskii et al., 2005)
Mutagen
in vitro construct
(Shidlovskii et al., 2005)
Progenitor genotype
e(y)3+tSa
(Shidlovskii et al., 2005)
Carried in construct
P{e(y)3ΔPHD}
Cytology
Description

Genomic fragment with a deletion of exons 10-12.

(Nikolenko et al., 2005)

The 3'-terminal 2622 bp of the P{e(y)3} genomic fragment has been deleted.

(Shidlovskii et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
e(y)3
Encoded product / tool
e(y)3
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant flies exhibit a repression of heterochromatin silencing.

      (Shidlovskii et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      e(y)3ΔPHD rescues e(y)3EMSl

      (Nikolenko et al., 2005)
      Partially rescues

      e(y)3ΔPHD partially rescues e(y)34

      (Nikolenko et al., 2005)

      e(y)3ΔPHD partially rescues e(y)3EMSl

      (Shidlovskii et al., 2005)
      Comments

      e(y)3ΔPHD rescues female fertility and viability in the e(y)34 mutant strain and also suppresses the enhancement of the y2 and yinr phenotypes caused by e(y)34.

      (Nikolenko et al., 2005)

      e(y)3ΔPHD rescues the viability and fertility of e(y)3EMSl mutants. However the repression of heterochromatin silencing phenotype remains.

      (Shidlovskii et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      e(y)3ΔPHD
      Name Synonyms
      Secondary FlyBase IDs
        References (2)