FlyBase Allele Report: Dmel\frtz[30]

General Information

Symbol

Dmel\frtz³⁰

Species

D. melanogaster

Name

FlyBase ID

FBal0179811

Feature type

allele

Associated gene

Dmel\frtz

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Collier et al., 2005)

Progenitor genotype

Cytology

Description

7bp deletion in exon 3 (CATGTGCCTGA > CAGA), plus an independent approximately 1kb deletion downstream. The mutant protein contains the N-terminal 493 residues plus 7 novel amino acids.

(Collier et al., 2005)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity | adult stage

(Wang et al., 2017)

visible | adult stage

(Wang et al., 2017)

Phenotype Manifest In

abdominal sternite bristle

(Wang et al., 2017)

Detailed Description

Statement

Reference

frtz³⁰ homozygous adults show hair polarity defects in abdominal bristles.

(Wang et al., 2017)

Strong allele.

(Collier et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

frtz³⁰ has visible | adult stage phenotype, non-enhanceable by ds^HMS00759/Scer\GAL4^ptc.PU

(Wang et al., 2017)

frtz³⁰ has abnormal planar polarity | adult stage phenotype, non-enhanceable by ds^HMS00759/Scer\GAL4^ptc.PU

(Wang et al., 2017)

frtz³⁰ has visible | adult stage phenotype, non-enhanceable by in^IH56/in^IH56

(Wang et al., 2017)

frtz³⁰ has abnormal planar polarity | adult stage phenotype, non-enhanceable by in^IH56/in^IH56

(Wang et al., 2017)

frtz³⁰ has visible | adult stage phenotype, non-enhanceable by fz¹/fz¹

(Wang et al., 2017)

frtz³⁰ has abnormal planar polarity | adult stage phenotype, non-enhanceable by fz¹/fz¹

(Wang et al., 2017)

NOT Enhancer of

Statement

Reference

frtz³⁰/frtz³⁰ is a non-enhancer of visible | adult stage phenotype of in^IH56

(Wang et al., 2017)

frtz³⁰/frtz³⁰ is a non-enhancer of abnormal planar polarity | adult stage phenotype of in^IH56

(Wang et al., 2017)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

frtz³⁰ has abdominal sternite bristle phenotype, non-enhanceable by in^IH56/in^IH56

(Wang et al., 2017)

frtz³⁰ has abdominal sternite bristle phenotype, non-enhanceable by fz¹/fz¹

(Wang et al., 2017)

frtz³⁰ has abdominal sternite bristle phenotype, non-enhanceable by ds^HMS00759/Scer\GAL4^ptc.PU

(Wang et al., 2017)

NOT Enhancer of

Statement

Reference

frtz³⁰/frtz³⁰ is a non-enhancer of abdominal sternite bristle phenotype of in^IH56

(Wang et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

frtz³⁰;fz¹ double mutant adults as well as frtz³⁰ mutants expressing ds^HMS00759 under the control of the Scer\GAL4^ptc.PU driver display hair polarity defects in abdominal bristles that are similarly severe as in frtz³⁰ single mutants. Similarly, the frtz³⁰/in^IH56 double mutants show abdominal bristle phenotype that is comparable to each of the single mutants.

(Wang et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

FK3521

(Collier et al., 2005)

fritz³⁰

(Collier et al., 2005)

frtz³⁰

(Wang et al., 2017)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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