FB2024_03 , released June 25, 2024
Allele: Dmel\orb2d01793
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General Information
Symbol
Dmel\orb2d01793
Species
D. melanogaster
Name
FlyBase ID
FBal0178569
Feature type
allele
Associated gene
Dmel\orb2
Associated Insertion(s)
P{XP}orb2d01793
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Xu et al., 2012)
Mutagen
P-element activity
(Gene Disruption Project members and Exelixis, 2005)
Progenitor genotype
Associated Insertion(s)
P{XP}orb2d01793
Cytology
Description

The P{XP}orb2d01793 insertion maps within both orb2 and CG43783 (the genes share some exons at the 5' end, including some coding sequence).

(FlyBase, 1996-)
Allele components
Component
Use(s)
Inserted element
P{XP}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Fertility of homozygous males is substantially impaired. Fertile orb2d01793/Df(3L)ED4416 males are occasionally recovered.

      (Xu et al., 2012)

      orb2d01793 mutants do not exhibit any obvious defects in locomotion and activity. Flies were able to return to a standing position following vortexing at a similar rate to wild type flies and show normal climbing ability.

      (Hafer et al., 2011)

      The rough eye phenotype observed in Fmr1sev.PW flies is suppressed in a orb2d01793/+ background.

      (Cziko et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      orb2d01793/orb2[+] is a suppressor of eye phenotype of Fmr1sev.PW

      (Cziko et al., 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      1793
      (Xu et al., 2012)
      orb2d01793
      (Cziko et al., 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)