FB2024_03 , released June 25, 2024
Allele: Dmel\Diap1UAS.Tag:MYC
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General Information
Symbol
Dmel\Diap1UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0177493
Feature type
allele
Associated gene
Dmel\Diap1
Associated Insertion(s)
Carried in Construct
P{UAS-Diap1.MYC}
Also Known As
UAS-myc::DIAP1
Key Links
Transgenic product class
wild_type
(Adachi-Yamada et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Adachi-Yamada et al., 2005)
Mutagen
in vitro construct
(Adachi-Yamada et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-Diap1.MYC}
Cytology
Description

UAS sequences drives expression of Diap1 tagged with Tag:MYC.

(Adachi-Yamada et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Diap1
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      S2 cells expressing thScer\UAS.T:Hsap\MYC under the control of Scer\GAL4Act5C.PI show an increased likelihood to have a serrate or stellate morphology, instead of the typical round morphology.

      (Oshima et al., 2006)

      Expression of thScer\UAS.T:Hsap\MYC under the control of Scer\GAL4ap-md544 does not lead to an increase in the number of apoptotic cells observed in eye/antennal discs.

      (Oshima, 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The excess branching of arista seen in flies that express ik2DN.Scer\UAS under the control of Scer\GAL4ap-md544 is enhanced by thScer\UAS.T:Hsap\MYC.

      Coexpression of thScer\UAS.T:Hsap\MYC and ik2DN.Scer\UAS under the control of Scer\GAL4Act5C.PI has an additive on S2 cell morphology.

      (Oshima et al., 2006)

      When thScer\UAS.T:Hsap\MYC and ssScer\UAS.A5 are co-expressed under the control of Scer\GAL4sd-SG29.1, an ectopic tarsus-like structure is is generated in the wing.

      (Adachi-Yamada et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference

      The loss of esg-positive cells as well as their aberrant morphology in the adult posterior midgut expressing GATAeGD4152 under the control of Scer\GAL4NP6267 (using tub-Gal80[ts] to limit the time of expression) cannot be rescued by the combined co-expression of both Diap1Scer\UAS.T:Hsap\MYC and BacA\p35Scer\UAS.cUa.

      (Okumura et al., 2016)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DIAP1OE
      (Oshima et al., 2006)
      Diap1Scer\UAS.T:Hsap\MYC
      Diap1UAS.Tag:MYC
      thScer\UAS.T:Hsap\MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (7)