Construct: Amino acid replacement: S292A. Amino acid replacement: T449A.
multidendritic neuron & dendrite, with Scer\GAL4477
multidendritic neuron & dendrite | supernumerary, with Scer\GAL4477
When trcS292A.T449A.Scer\UAS.T:Zzzz\FLAG is driven by Scer\GAL4477 an increase in terminal branches is seen in ddaC dendrites. Tiling defects are also seen.
trcS292A.T449A.UAS.Tag:FLAG/Scer\GAL4ppk.PU is an enhancer of abnormal neuroanatomy | third instar larval stage phenotype of Sema2bf02042/Df(2R)Sema2b-C4
trcS292A.T449A.UAS.Tag:FLAG/Scer\GAL4ppk.PU is an enhancer of larval multidendritic class IV neuron | third instar larval stage phenotype of Sema2bf02042/Df(2R)Sema2b-C4
Expression of trcS292A.T449A.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4ppk.PU in the Sema-2bf02042/Df(2R)Sema-2b-C4 mutant larvae background exacerbated the increased dendritic crossing phenotype in the class IV da neurons displayed by the Sema-2bf02042/Df(2R)Sema-2b-C4 mutants.
trcS292A.T449A.UAS.Tag:FLAG/Scer\GAL4477 fails to rescue trc1