FB2024_03 , released June 25, 2024
Allele: Dmel\trcUAS.Tag:FLAG
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General Information
Symbol
Dmel\trcUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0177396
Feature type
allele
Associated gene
Dmel\trc
Associated Insertion(s)
Carried in Construct
P{UAS-trc.FLAG}
Also Known As
UAS-trc
Key Links
Transgenic product class
wild_type
(Emoto et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Emoto et al., 2004)
Mutagen
in vitro construct
(Emoto et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-trc.FLAG}
Cytology
Description

UASt sequences drive expression of trc tagged with Tag:FLAG.

(Emoto et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
trc
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      multidendritic neuron & dendrite, with Scer\GAL4477

      (Emoto et al., 2004)

      multidendritic neuron & dendrite | supernumerary, with Scer\GAL4477

      (Emoto et al., 2004)
      Detailed Description
      Statement
      Reference

      When trcScer\UAS.T:Zzzz\FLAG is driven by Scer\GAL4477 a slight reduction of branch numbers are seen in ddaC neurons.

      (Emoto et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Suppressor of
      Statement
      Reference

      Scer\GAL4elav-C155/trcUAS.Tag:FLAG is a suppressor | partially of abnormal neuroanatomy phenotype of hpoMGH4

      (Emoto et al., 2006)
      Phenotype Manifest In
      Enhancer of
      Suppressor of
      Statement
      Reference

      Scer\GAL4elav-C155/trcUAS.Tag:FLAG is a suppressor | partially of multidendritic dendrite phenotype of hpoMGH4

      (Emoto et al., 2006)

      trcUAS.Tag:FLAG, Scer\GAL4477 is a suppressor | partially of multidendritic neuron & dendrite phenotype of Rac1UAS.cLa, Scer\GAL4477

      (Emoto et al., 2004)

      trcUAS.Tag:FLAG, Scer\GAL4477 is a suppressor | partially of multidendritic neuron & dendrite | supernumerary phenotype of Rac1UAS.cLa, Scer\GAL4477

      (Emoto et al., 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of trcScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4ppk.PU in the Sema-2bf02042/Df(2R)Sema-2b-C4 mutant larvae background exacerbated the increased dendritic crossing phenotype in the class IV da neurons displayed by the Sema-2bf02042/Df(2R)Sema-2b-C4 mutants.

      (Meltzer et al., 2016)

      Overexpression of trcScer\UAS.T:Zzzz\FLAG, under the control of Scer\GAL4elav-C155 in hpoMGH4 MARCM clones partially suppresses the dendritic tiling defects in class IV neurons.

      (Emoto et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      trcUAS.Tag:FLAG/Scer\GAL4477 rescues trc1

      (Emoto et al., 2004)
      Comments

      When trcScer\UAS.T:Zzzz\FLAG is driven by a class IV neuron-specific driver, the dendritic branching and tiling defects are largely rescued/.

      (Emoto et al., 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in plasmid "pUAST-Trc-FLAG" and transfected into S2 cells to study the interaction of the expressed product with the fry protein.

      (He et al., 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      trcScer\UAS.T:Zzzz\FLAG
      trcUAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (5)