FB2024_03 , released June 25, 2024
Allele: Dmel\LarΔFn123.UAS
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General Information
Symbol
Dmel\LarΔFn123.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0160253
Feature type
allele
Associated gene
Dmel\Lar
Associated Insertion(s)
Carried in Construct
P{UAS-Lar.ΔFn123}
Key Links
Transgenic product class
inframe_deletion
(Krueger et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Krueger et al., 2003)
Mutagen
in vitro construct
(Krueger et al., 2003)
Progenitor genotype
LarUAS.cKa
(Krueger et al., 2003)
Carried in construct
P{UAS-Lar.ΔFn123}
Cytology
Description

Deletion removing FnIII domains 1-3 of Lar.

(Krueger et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Lar
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Increases the penetrance of the round oocyte phenotype of Lar13.2/Lar5.5 escapers, when expression driven by Scer\GAL4T155.

      (Krueger et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav-C155/LarΔFn123.UAS rescues LarC12/Lar2127

      (Hofmeyer and Treisman, 2009)
      Partially rescues

      Scer\GAL4elav-C155/LarΔFn123.UAS partially rescues Lar5.5/Lar13.2

      (Krueger et al., 2003)
      Comments

      Expression of LarΔFn123.Scer\UAS under the control of Scer\GAL4elav-C155 in LarC12/Lar2127 mutant eye discs rescues axon mistargeting.

      (Hofmeyer and Treisman, 2009)

      Partial rescue statement based on rescue of lethality.

      (Krueger et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      LarΔFn123.Scer\UAS
      LarΔFn123.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)