FlyBase Allele Report: Dmel\crol[unspecified]

General Information

Symbol

Dmel\crol^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0155430

Feature type

allele

Associated gene

Dmel\crol

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell death | larval stage, with Scer\GAL4^ey.PH

(Schneiderman et al., 2010)

increased occurrence of cell division | larval stage, with Scer\GAL4^ey.PH

(Schneiderman et al., 2010)

Phenotype Manifest In

eye disc morphogenetic furrow, with Scer\GAL4^ey.PH

(Schneiderman et al., 2010)

Detailed Description

Statement

Reference

Over-expression of crol^unspecified driven by Scer\GAL4^ey.PH causes a substantial increase in the number of mitotic cells on both sides of the morphogenetic furrow. This is accompanied by increased cell death in these zones.

(Schneiderman et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, bw^D, crol^unspecified has abnormal eye color | dominant phenotype, suppressible by Hsap\CDKN1A^GMR.PH

(Schneiderman et al., 2010)

Other

Statement

Reference

CycB[+]/CycB², Scer\GAL4^unspecified, bw^D, crol^unspecified has abnormal eye color | dominant phenotype

(Schneiderman et al., 2010)

E(zip)31-6^31-6, crol^unspecified has viable phenotype

(Bayer et al., 2003)

E(zip)12-5^12-5, crol^unspecified has viable phenotype

(Bayer et al., 2003)

E(zip)18-5^18-5, crol^unspecified has viable phenotype

(Bayer et al., 2003)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, bw^D, crol^unspecified has eye phenotype, suppressible by Hsap\CDKN1A^GMR.PH

(Schneiderman et al., 2010)

Other

Statement

Reference

Scer\GAL4^unspecified, Usp47^LA5.3, bw^D, crol^unspecified has eye phenotype

(Schneiderman et al., 2010)

CycB[+]/CycB², Scer\GAL4^unspecified, bw^D, crol^unspecified has eye phenotype

(Schneiderman et al., 2010)

Scer\GAL4^unspecified, bw^D, crol^unspecified, jim^LA3.1 has eye phenotype

(Schneiderman et al., 2010)

CG8036^LA3.2, Scer\GAL4^unspecified, bw^D, crol^unspecified has eye phenotype

(Schneiderman et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

CycB² dominantly reduces the area of sectors of increased pigmentation in a bw^D/+ genetic background resulting from the over-expression of crol^unspecified driven by Scer\GAL4^unspecified.

Contemporaneous expression of jim^LA3.1 with crol^unspecified driven by Scer\GAL4^unspecified reduces the size and frequency of sectors of increased pigmentation in a bw^D/+ genetic background, but the background speckled variegation remains unchanged.

Contemporaneous expression of CG8036^LA3.2 with crol^unspecified driven by Scer\GAL4^unspecified reduces the size and frequency of sectors of increased pigmentation in a bw^D/+ genetic background, but the background speckled variegation remains unchanged.

Contemporaneous expression of CG10630^LA4.4 with crol^unspecified driven by Scer\GAL4^unspecified reduces the size and frequency of sectors of increased pigmentation in a bw^D/+ genetic background, but the background speckled variegation remains unchanged.

Contemporaneous expression of Ubp64E^LA5.3 with crol^unspecified driven by Scer\GAL4^unspecified increases the size or frequency of sectors of increased pigmentation in a bw^D/+ genetic background, but the background speckled variegation remains unchanged.

(Schneiderman et al., 2010)

Double heterozygotes with E(zip)12-5^12-5, E(zip)18-5^18-5 or E(zip)31-6^31-6 are fully viable and have wild-type leg morphology.

(Bayer et al., 2003)

Xenogenetic Interactions

Statement

Reference

The increased eye pigmentation in bw^D/+ heterozygotes resulting from the mis-expression of crol^unspecified driven by Scer\GAL4^GMR.PF is suppressed by Hsap\CDKN1A^GMR.PH.

(Schneiderman et al., 2010)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

crol^unspecified

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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