FB2024_03 , released June 25, 2024
Allele: Dmel\Vangsev.PR
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General Information
Symbol
Dmel\Vangsev.PR
Species
D. melanogaster
Name
sevenless promoter construct of Rawls
FlyBase ID
FBal0147327
Feature type
allele
Associated gene
Dmel\Vang
Associated Insertion(s)
Carried in Construct
P{sev-stbm.R}
Also Known As
sev-stbm
Key Links
Transgenic product class
wild_type
(Rawls and Wolff, 2003)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Rawls and Wolff, 2003)
Mutagen
in vitro construct
(Rawls and Wolff, 2003)
Progenitor genotype
Carried in construct
P{sev-stbm.R}
Cytology
Description

The sev promoter drives expression of Vang.

(Rawls and Wolff, 2003)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
Vang
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying one copy of Vangsev.PR show polarity defects in 15.4% of ommatidia.

      (Rawls et al., 2007)

      In mutant eyes, about 10% of ommatidia display errors in polarity; anterior posterior polarity defects, dorsal ventral defects, and defects in R3 and R4 are seen.

      (Rawls and Wolff, 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Vangsev.PR has ommatidium phenotype, enhanceable by bdgKG07083/CG8291[+]

      (Rawls et al., 2007)

      Vangsev.PR has ommatidium phenotype, enhanceable by bdg164/bdg[+]

      (Rawls et al., 2007)

      Vangsev.PR has ommatidium phenotype, enhanceable by Df(2L)N22-14

      (Rawls and Wolff, 2003)

      Vangsev.PR has ommatidium phenotype, enhanceable by Df(2R)pk78k

      (Rawls and Wolff, 2003)

      Vangsev.PR has ommatidium phenotype, enhanceable by pk1

      (Rawls and Wolff, 2003)

      Vangsev.PR has ommatidium phenotype, enhanceable by stan192

      (Rawls and Wolff, 2003)

      Vangsev.PR has ommatidium phenotype, enhanceable by stanE59

      (Rawls and Wolff, 2003)

      Vangsev.PR has ommatidium phenotype, enhanceable by stanfrz3

      (Rawls and Wolff, 2003)

      Vangsev.PR has ommatidium phenotype, enhanceable by Df(2L)s1402

      (Rawls and Wolff, 2003)

      Vangsev.PR has ommatidium phenotype, enhanceable by Df(2R)Drlrv5

      (Rawls and Wolff, 2003)

      Vangsev.PR has ommatidium phenotype, enhanceable by Df(2R)E3363

      (Rawls and Wolff, 2003)

      Vangsev.PR has ommatidium phenotype, enhanceable by Df(2R)Jp4

      (Rawls and Wolff, 2003)
      Suppressed by
      Statement
      Reference

      Vangsev.PR has ommatidium phenotype, suppressible by bdg[+]/bdgGMREP

      (Rawls et al., 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The ommatidial polarity defects caused by Vangsev.PR are significantly suppressed by one copy of bdgGMREP and are dominantly enhanced by bdgKG07083 or bdg164.

      (Rawls et al., 2007)

      The addition of stanfrz3, stan192 or stanE59 enhances the ommatidium polarity phenotype seen in Vangsev.PR animals about three-fold. The addition of Df(2R)Drlrv5 enhances the ommatidium polarity phenotype seen in Vangsev.PR animals about 2.5 fold. The addition of pk1 or Df(2R)E3363 enhances the ommatidium polarity phenotype seen in Vangsev.PR animals about three fold. The addition of Df(2L)N22-14 enhances the ommatidium polarity phenotype seen in Vangsev.PR animals about three fold. The addition of Df(2L)s1402 enhances the ommatidium polarity phenotype seen in Vangsev.PR animals about two fold. The addition of Df(2R)pk78k enhances the ommatidium polarity phenotype seen in Vangsev.PR animals about three fold. The addition of Df(2R)Jp4 enhances the ommatidium polarity phenotype seen in Vangsev.PR animals about 2.5 fold.

      (Rawls and Wolff, 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Vangsev.PR
      Name Synonyms
      sevenless promoter construct of Rawls
      (Rawls and Wolff, 2003)
      Secondary FlyBase IDs
        References (2)