Expression of lokScer\UAS.cPa under the control of Scer\GAL4GMR.PF does not cause obvious eye degeneration.
Expression of lokScer\UAS.cPa under the control of Scer\GAL4GMR.PF does not result in an overt phenotype in the eye and no apoptotic cells are detected in third larval instar eye discs. Irradiated eye discs from larvae expressing lokScer\UAS.cPa under the control of Scer\GAL4GMR.PF posterior to the morphogenetic furrow show high numbers of apoptotic cells in this area (wild-type irradiated discs have an increased number of apoptotic cells both anterior and posterior to the furrow).
Scer\GAL4GMR.PF/lokUAS.cPa is an enhancer of visible phenotype of Scer\GAL4GMR.PF, p53UAS.cPa
Scer\GAL4GMR.PF/lokUAS.cPa is a non-enhancer of visible | adult stage phenotype of Scer\GAL4GMR.PF, Zzzz\CAGQ108.UAS.Tag:MYC,Tag:FLAG
lokUAS.cPa, Scer\GAL4GMR.PF is a non-enhancer of visible | adult stage phenotype of Hsap\APPArctic.Aβ42.UAS.Tag:SS(rPENK), Scer\GAL4GMR.PF
Scer\GAL4GMR.PF/lokUAS.cPa is a non-enhancer of visible | adult stage phenotype of Scer\GAL4GMR.PF, par-1UAS.Tag:MYC
Scer\GAL4GMR.PF/lokUAS.cPa is a non-enhancer of visible phenotype of Scer\GAL4GMR.PF, p53S4A.UAS
Scer\GAL4GMR.PF/lokUAS.cPa is a non-suppressor of visible phenotype of Scer\GAL4GMR.PF, p53S4A.UAS
Scer\GAL4GMR.PF, lokUAS.cPa, p53UAS.cPa has increased cell death phenotype
Scer\GAL4GMR.PF/lokUAS.cPa is an enhancer of eye phenotype of Scer\GAL4GMR.PF, p53UAS.cPa
Scer\GAL4GMR.PF/lokUAS.cPa is a non-enhancer of eye phenotype of Scer\GAL4GMR.PF, Zzzz\CAGQ108.UAS.Tag:MYC,Tag:FLAG
lokUAS.cPa, Scer\GAL4GMR.PF is a non-enhancer of eye phenotype of Hsap\APPArctic.Aβ42.UAS.Tag:SS(rPENK), Scer\GAL4GMR.PF
Scer\GAL4GMR.PF/lokUAS.cPa is a non-enhancer of eye phenotype of Scer\GAL4GMR.PF, par-1UAS.Tag:MYC
Scer\GAL4GMR.PF/lokUAS.cPa is a non-enhancer of eye phenotype of Scer\GAL4GMR.PF, p53S4A.UAS
Scer\GAL4GMR.PF/lokUAS.cPa is a non-suppressor of eye phenotype of Scer\GAL4GMR.PF, p53S4A.UAS
Co-expression of lokScer\UAS.cPa and p53Scer\UAS.cPa under the control of Scer\GAL4GMR.PF results in almost complete loss of the eye. Excessive apoptosis is seen in third larval instar eye discs in these animals. The small eye phenotype caused by expression of p53S4A.Scer\UAS under the control of Scer\GAL4GMR.PF is not altered by coexpression of lokScer\UAS.cPa.
Expression of lokScer\UAS.cPa does not enhance the eye depigmentation phenotype seen when Zzzz\CAGQ108.Scer\UAS.T:Hsap\MYC,T:Zzzz\FLAG is expressed under the control of Scer\GAL4GMR.PF.
Expression of lokScer\UAS.cPa does not enhance the eye degeneration phenotype seen when Hsap\APPAβ1-42.Scer\UAS.Arc is expressed under the control of Scer\GAL4GMR.PF.
Co-expression of Hsap\MAPTScer\UAS.S262A and lokScer\UAS.cPa under the control of Scer\GAL4GMR.PF has no effect on external eye size.
Expression of lokScer\UAS.cPa does not enhance the eye degeneration phenotype seen when par-1Scer\UAS.T:Hsap\MYC is expressed under the control of Scer\GAL4GMR.PF.
Carried in plasmid "pUAST-dm-chk2-wt", transfected into S2 cells with a driver construct and used in transcription activation assays.