FlyBase Allele Report: Dmel\N[ΔLNR.lexA.UAS]

General Information

Symbol

Dmel\N^{ΔLNR.lexA.UAS}

Species

D. melanogaster

Name

FlyBase ID

FBal0130872

Feature type

allele

Associated gene

Dmel\N

Associated Insertion(s)

Carried in Construct

P{UAS-N.ΔLNR.LexA}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Lieber et al., 2002)

Progenitor genotype

N^lexA.UAS

(Lieber et al., 2002)

Carried in construct

P{UAS-N.ΔLNR.LexA}

Cytology

Description

Amino acids 1482-1593 have been deleted.

(Lieber et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size, with Scer\GAL4^Act.PU

(Leonardi et al., 2011)

Phenotype Manifest In

presumptive embryonic/larval central nervous system, with Scer\GAL4^da.G32

(Lieber et al., 2002)

wing disc | somatic clone | third instar larval stage, with Scer\GAL4^Act.PU

(Leonardi et al., 2011)

Detailed Description

Statement

Reference

Expression of N^{Scer\UAS.ΔLNR.T:Ecol\lexA} in MARCM clones under the control of Scer\GAL4^Act.PU engenders tissue overgrowth.

(Leonardi et al., 2011)

When N^{Scer\UAS.ΔLNR.T:Ecol\lexA} is driven by Scer\GAL4^da.G32, gaps in the embryonic central nervous system are seen, characteristic of an antineurogenic phenotype.

(Lieber et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

N^{ΔLNR.lexA.UAS}, Scer\GAL4^Act.PU has abnormal size phenotype, suppressible by rumi^Δ26

(Leonardi et al., 2011)

Phenotype Manifest In

Suppressed by

Statement

Reference

N^{ΔLNR.lexA.UAS}, Scer\GAL4^Act.PU has wing disc | somatic clone | third instar larval stage phenotype, suppressible by rumi^Δ26

(Leonardi et al., 2011)

N^{ΔLNR.lexA.UAS}, Scer\GAL4^da.G32 has presumptive embryonic/larval central nervous system phenotype, suppressible | partially by kuz^e29-4

(Lieber et al., 2002)

N^{ΔLNR.lexA.UAS}, Scer\GAL4^da.G32 has presumptive embryonic/larval central nervous system phenotype, suppressible | partially by Delta^X

(Lieber et al., 2002)

Suppressor of

Statement

Reference

N^{ΔLNR.lexA.UAS}/Scer\GAL4^da.G32 is a suppressor of presumptive embryonic/larval central nervous system | germline clone phenotype of kuz^e29-4

(Lieber et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

rumi^Δ26 fully suppresses the N^{Scer\UAS.ΔLNR.T:Ecol\lexA} wing imaginal disc phenotypes.

(Leonardi et al., 2011)

The embryonic central nervous system seen in Dl^X, N^{Scer\UAS.ΔLNR.T:Ecol\lexA}, Scer\GAL4^da.G32 animals is weaker than that seen in N^{Scer\UAS.ΔLNR.T:Ecol\lexA}, Scer\GAL4^da.G32 animals alone. The addition of kuz^e29-4 also partially suppresses the phenotype.

(Lieber et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

LNR^LexA

(Lieber et al., 2002)

N^{Scer\UAS.ΔLNR.T:Ecol\lexA}

N^{ΔLNR.lexA.UAS}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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