FB2024_03 , released June 25, 2024
Allele: Dmel\ultA1
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General Information
Symbol
Dmel\ultA1
Species
D. melanogaster
Name
FlyBase ID
FBal0124918
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Shows a multiple wing hair phenotype.

    If somatic clones are induced earlier than second instar larvae, no clones survive to adulthood. If induced during the third instar many clones are seen, none larger than 10 cells in size. When clones are seen in the wing blade, a number of different phenotypes are seen in wing hairs. Hairs can be longer than normal. Hairs are often split distally, if this happens they are pointed 30 to 60o apart from one another and are usually approximately normal in length, though some can be significantly longer than normal. Some clones produce four to six wing hairs, of often variable length, in a single cell - the wing is frequently kinked in the region of such cells. Occasionally cells are seen that produce more than a dozen relatively normal-sized hairs. Somatic clones in the wing also leads to splitting of bristles in the wing margin is also seen, these bristles are also larger than normal. There is no evidence of socket cells surrounding these "bristles". Somatic clones in the pupal wing have larger cells with larger nuclei than wild-type that may be polyploid. Also prehairs are formed over a large region of the cell in these clones, unlike wild-type where they are restricted to the distal most part of the cell. Reducing the cell size in wings with mutant somatic clones by starvation produced a partial suppression of the phenotypes seen.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Enhanced by
    Statement
    Reference

    ultA1 has wing hair phenotype, enhanceable by trc1

    ultA1 has wing hair | somatic clone phenotype, enhanceable by in1

    ultA1 has wing hair | somatic clone phenotype, enhanceable by mwh1

    Enhancer of
    Statement
    Reference

    ultA1 is an enhancer of wing hair | somatic clone phenotype of in1

    ultA1 is an enhancer of wing hair | somatic clone phenotype of mwh1

    Additional Comments
    Genetic Interactions
    Statement
    Reference

    In somatic clones of cells that are homozygous for both mwh1 and ultA1, or in1 and ultA1, an increase is seen in the average number of wing hairs per cell.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    ultA1
    Name Synonyms
    Secondary FlyBase IDs
      References (2)