FlyBase Allele Report: Scer\GAL4[Or47b.7.467]

General Information

Symbol

Scer\GAL4^Or47b.7.467

Species

S. cerevisiae

Name

FlyBase ID

FBal0118362

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{Or47b-GAL4.7.467}

Also Known As

Or47b-Gal4, Or47bGal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Vosshall et al., 2000)

Progenitor genotype

Carried in construct

P{Or47b-GAL4.7.467}

Cytology

Description

7.467kb of Or47b promoter sequences regulate expression of a GAL4 driver.

(Vosshall et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

Or47b

Or47b_Or47bVosshall

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

antenna

(Hummel and Zipursky, 2004, Suh et al., 2004)

antennal lobe glomerulus VA1 | restricted

(Jhaveri et al., 2004, Ang et al., 2003, Hummel et al., 2003)

antenna | restricted

(Jhaveri et al., 2004, Ang et al., 2003, Hummel et al., 2003, Wang et al., 2003, Vosshall et al., 2000)

sensory neuron | subset

(Hummel and Zipursky, 2004, Jhaveri et al., 2004, Suh et al., 2004, Ang et al., 2003, Hummel et al., 2003, Wang et al., 2003, Vosshall et al., 2000)

sensory neuron of antenna | subset

(Hummel and Zipursky, 2004, Jhaveri et al., 2004, Suh et al., 2004, Ang et al., 2003, Hummel et al., 2003, Wang et al., 2003, Vosshall et al., 2000)

antennal lobe glomerulus VM1 | restricted

(Wang et al., 2003)

adult olfactory receptor neuron Or47b

(Fishilevich and Vosshall, 2005)

antennal lobe glomerulus VA1v

(Fishilevich and Vosshall, 2005)

adult olfactory receptor neuron | subset

(Suh et al., 2004)

adult antennal lobe glomerulus | restricted

(Hummel and Zipursky, 2004)

adult antennal lobe glomerulus | subset

(Vosshall et al., 2000)

Additional Information

Statement

Reference

Drives expression in adult olfactory receptor neuron Or47b, which projects to antennal lobe glomerulus VA1v.

(FlyBase Curators, 2017)

Or47b expressing neurons project to both the ipsilateral and contralateral VA1 glomeruli.

(Jhaveri et al., 2004)

Sensory neurons expressing Or47b innervate the VA1lm glomerulus.

(Wang et al., 2003)

Sensory neurons expressing Or47b project into the VA1lm glomerulus of the antennal lobe.

(Ang et al., 2003)

Axons of Or47b-expressing neurons project to the VA1 l/m glomerulus.

(Hummel et al., 2003)

Expression of Or47b is observed in ~50 antennal neurons that reside in the lateral distal edge of the antenna. These neurons project axons that converge on a single large glomerulus that lies at the ventral lateral edge of the antennal lobe.

(Vosshall et al., 2000)

Marker for

adult olfactory receptor neuron Or47b

(Hummel and Zipursky, 2004, Jhaveri et al., 2004, Suh et al., 2004, Ang et al., 2003, Hummel et al., 2003)

antennal lobe glomerulus VM1

(Wang et al., 2003)

Reflects expression of

Or47b

(Fishilevich and Vosshall, 2005, Hummel and Zipursky, 2004, Jhaveri et al., 2004, Suh et al., 2004, Ang et al., 2003, Hummel et al., 2003, Wang et al., 2003, Vosshall et al., 2000)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal chemosensory behavior | adult stage, with fru^RNAi.B.UAS

(Zhang et al., 2020)

abnormal chemosensory behavior | adult stage, with fru^{RNAi.C.UAS.cvPa}

(Zhang et al., 2020)

abnormal chemosensory behavior | adult stage, with fru^UAS.MC

(Zhang et al., 2020)

abnormal chemosensory behavior | adult stage | female, with fru^UAS.MB, fru^UAS.MC

(Zhang et al., 2020)

abnormal chemosensory behavior | adult stage | male, with fru^UAS.MB

(Zhang et al., 2020)

abnormal courtship behavior | conditional, with nej^RNAi.UAS.cSa

(Sethi et al., 2019)

abnormal neuroanatomy, with Cbeta\DT^A-I.UAS

(Berdnik et al., 2006)

abnormal neuroanatomy, with Rcom\RT^A.UAS

(Berdnik et al., 2006)

abnormal neurophysiology | adult stage, with fru^RNAi.B.UAS

(Zhang et al., 2020)

abnormal neurophysiology | adult stage, with fru^{RNAi.C.UAS.cvPa}

(Zhang et al., 2020)

abnormal neurophysiology | adult stage, with fru^UAS.MC

(Zhang et al., 2020)

abnormal neurophysiology | adult stage | conditional, with CaMKI^JF02268

(Sethi et al., 2019)

abnormal neurophysiology | adult stage | conditional, with fru^RNAi.UAS.1

(Sethi et al., 2019)

abnormal neurophysiology | adult stage | conditional, with fru^UAS.P1

(Sethi et al., 2019)

abnormal neurophysiology | adult stage | conditional, with Met^KK104562

(Sethi et al., 2019)

abnormal neurophysiology | adult stage | conditional, with nej^RNAi.UAS.cSa

(Sethi et al., 2019)

abnormal neurophysiology | adult stage | conditional, with Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}, fru^TOE.GS02668

(Sethi et al., 2019)

abnormal neurophysiology | adult stage | conditional, with tra^UAS.cFa

(Sethi et al., 2019)

abnormal neurophysiology | adult stage | female, with fru^UAS.MB, fru^UAS.MC

(Zhang et al., 2020)

abnormal neurophysiology | adult stage | male, with fru^UAS.MB

(Zhang et al., 2020)

increased cell number | P-stage, with ths^UAS.cUa

(Wu et al., 2017)

Phenotype Manifest In

adult ensheathing glial cell | P-stage | increased number, with ths^UAS.cUa

(Wu et al., 2017)

adult olfactory receptor neuron Or47b, with fru^RNAi.B.UAS

(Zhang et al., 2020)

adult olfactory receptor neuron Or47b, with fru^{RNAi.C.UAS.cvPa}

(Zhang et al., 2020)

adult olfactory receptor neuron Or47b, with fru^UAS.MC

(Zhang et al., 2020)

adult olfactory receptor neuron Or47b, with Ten-a^GD8834

(Mosca and Luo, 2014)

adult olfactory receptor neuron Or47b, with α-Spec^RNAi.UAS

(Mosca and Luo, 2014)

adult olfactory receptor neuron Or47b, with β-Spec^RNAi.UAS

(Mosca and Luo, 2014)

adult olfactory receptor neuron Or47b | adult stage | conditional, with CaMKI^JF02268

(Sethi et al., 2019)

adult olfactory receptor neuron Or47b | adult stage | conditional, with fru^RNAi.UAS.1

(Sethi et al., 2019)

adult olfactory receptor neuron Or47b | adult stage | conditional, with fru^UAS.P1

(Sethi et al., 2019)

adult olfactory receptor neuron Or47b | adult stage | conditional, with Met^KK104562

(Sethi et al., 2019)

adult olfactory receptor neuron Or47b | adult stage | conditional, with nej^RNAi.UAS.cSa

(Sethi et al., 2019)

adult olfactory receptor neuron Or47b | adult stage | conditional, with Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}, fru^TOE.GS02668

(Sethi et al., 2019)

adult olfactory receptor neuron Or47b | adult stage | conditional, with tra^UAS.cFa

(Sethi et al., 2019)

adult olfactory receptor neuron Or47b | female, with fru^UAS.MB, fru^UAS.MC

(Zhang et al., 2020)

adult olfactory receptor neuron Or47b | male, with fru^UAS.MB

(Zhang et al., 2020)

antennal lobe glomerulus VA1, with Rcom\RT^A.UAS

(Berdnik et al., 2006)

antennal lobe glomerulus VA1d | P-stage, with ths^UAS.cUa

(Wu et al., 2017)

antennal lobe glomerulus VA1v | P-stage, with ths^UAS.cUa

(Wu et al., 2017)

olfactory neuron & antennal glomerulus VA1, with Cbeta\DT^A-I.UAS

(Berdnik et al., 2006)

olfactory neuron & antennal glomerulus VA1, with Rcom\RT^A.UAS

(Berdnik et al., 2006)

presynaptic active zone | adult stage, with Ten-a^GD8834

(Mosca and Luo, 2014)

presynaptic active zone | adult stage, with α-Spec^RNAi.UAS

(Mosca and Luo, 2014)

presynaptic active zone | adult stage, with β-Spec^RNAi.UAS

(Mosca and Luo, 2014)

synapse | adult stage, with Ten-a^GD8834

(Mosca and Luo, 2014)

synapse | adult stage, with α-Spec^RNAi.UAS

(Mosca and Luo, 2014)

synapse | adult stage, with β-Spec^RNAi.UAS

(Mosca and Luo, 2014)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^Or47b.7.467, fru^UAS.MB has abnormal chemosensory behavior | adult stage | male phenotype, non-enhanceable by Met¹

(Zhang et al., 2020)

Scer\GAL4^Or47b.7.467, fru^UAS.MB has abnormal neurophysiology | adult stage | male phenotype, non-enhanceable by Met¹

(Zhang et al., 2020)

Suppressed by

Statement

Reference

Scer\GAL4^Or47b.7.467, fru^UAS.MB has abnormal chemosensory behavior | male | adult stage phenotype, suppressible by ppk25^Δ5-22

(Zhang et al., 2020)

Scer\GAL4^Or47b.7.467, fru^UAS.MB has abnormal neurophysiology | male | adult stage phenotype, suppressible by ppk25^Δ5-22

(Zhang et al., 2020)

Met^KK104562, Scer\GAL4^Or47b.7.467 has abnormal neurophysiology | adult stage | conditional phenotype, suppressible by fru^TOE.GS02668/Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}, Scer\GAL4^Or47b.7.467

(Sethi et al., 2019)

Scer\GAL4^Or47b.7.467, nej^RNAi.UAS.cSa has abnormal neurophysiology | adult stage | conditional phenotype, suppressible by fru^TOE.GS02668/Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}/Scer\GAL4^Or47b.7.467

(Sethi et al., 2019)

NOT suppressed by

Statement

Reference

Scer\GAL4^Or47b.7.467, fru^UAS.MB has abnormal chemosensory behavior | male | adult stage phenotype, non-suppressible by Met¹

(Zhang et al., 2020)

Scer\GAL4^Or47b.7.467, fru^UAS.MB has abnormal neurophysiology | male | adult stage phenotype, non-suppressible by Met¹

(Zhang et al., 2020)

Suppressor of

Statement

Reference

fru^TOE.GS02668/Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}, Scer\GAL4^Or47b.7.467 is a suppressor of abnormal neurophysiology | adult stage | conditional phenotype of Met^KK104562, Scer\GAL4^Or47b.7.467

(Sethi et al., 2019)

fru^TOE.GS02668, Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}, Scer\GAL4^Or47b.7.467 is a suppressor of abnormal neurophysiology | adult stage | conditional phenotype of Scer\GAL4^Or47b.7.467, nej^RNAi.UAS.cSa

(Sethi et al., 2019)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^Or47b.7.467, fru^UAS.MB has adult olfactory receptor neuron Or47b | male phenotype, non-enhanceable by Met¹

(Zhang et al., 2020)

Scer\GAL4^Or47b.7.467, fru^UAS.MB has adult olfactory receptor neuron Or47b | male phenotype, non-enhanceable by ppk25^Δ5-22

(Zhang et al., 2020)

Suppressed by

Statement

Reference

Scer\GAL4^Or47b.7.467, nej^RNAi.UAS.cSa has adult olfactory receptor neuron Or47b | adult stage | conditional phenotype, suppressible by fru^TOE.GS02668/Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}/Scer\GAL4^Or47b.7.467

(Sethi et al., 2019)

Met^KK104562, Scer\GAL4^Or47b.7.467 has adult olfactory receptor neuron Or47b | adult stage | conditional phenotype, suppressible by fru^TOE.GS02668/Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}, Scer\GAL4^Or47b.7.467

(Sethi et al., 2019)

NOT suppressed by

Statement

Reference

Scer\GAL4^Or47b.7.467, fru^UAS.MB has adult olfactory receptor neuron Or47b | male phenotype, non-suppressible by Met¹

(Zhang et al., 2020)

Scer\GAL4^Or47b.7.467, fru^UAS.MB has adult olfactory receptor neuron Or47b | male phenotype, non-suppressible by ppk25^Δ5-22

(Zhang et al., 2020)

Suppressor of

Statement

Reference

fru^TOE.GS02668, Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}, Scer\GAL4^Or47b.7.467 is a suppressor of adult olfactory receptor neuron Or47b | adult stage | conditional phenotype of Scer\GAL4^Or47b.7.467, nej^RNAi.UAS.cSa

(Sethi et al., 2019)

fru^TOE.GS02668/Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}, Scer\GAL4^Or47b.7.467 is a suppressor of adult olfactory receptor neuron Or47b | adult stage | conditional phenotype of Met^KK104562, Scer\GAL4^Or47b.7.467

(Sethi et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Or47b^UAS.Tag:MYC/Scer\GAL4^Or47b.7.467 rescues Or47b³

(Dweck et al., 2015)

Partially rescues

Ten-a^UAS.cHa/Scer\GAL4^Or47b.7.467 partially rescues Df(1)Ten-a

(Mosca and Luo, 2014)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

9984

w^*; P{Or47b-GAL4.7.467}15.6

9983

w^*; P{Or47b-GAL4.7.467}Bacc^15.5A

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^Or47b.7.467

Name Synonyms

Secondary FlyBase IDs

References (45)

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