FlyBase Allele Report: Dmel\hh[UAS.cKa]

General Information

Symbol

Dmel\hh^UAS.cKa

Species

D. melanogaster

Name

FlyBase ID

FBal0104603

Feature type

allele

Associated gene

Dmel\hh

Associated Insertion(s)

Carried in Construct

P{UAS-hh.K}

Also Known As

UAS-hh

Key Links

Transgenic product class

wild_type

(Suzuki and Saigo, 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Suzuki and Saigo, 2000)

Mutagen

in vitro construct

(Suzuki and Saigo, 2000)

Progenitor genotype

Carried in construct

P{UAS-hh.K}

Cytology

Description

UAS regulatory sequences drive expression of hh.

(Suzuki and Saigo, 2000)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Bolwig organ, with Scer\GAL4^da.G32

(Suzuki and Saigo, 2000)

Bolwig organ, with Scer\GAL4^h-1J3

(Suzuki and Saigo, 2000)

Detailed Description

Statement

Reference

Expression of hh^Scer\UAS.cKa under the control of either Scer\GAL4^h-1J3 or Scer\GAL4^da.G32 results in a 2-3 fold increase in the number of Bolwig's organ neurons compared to wild type.

(Suzuki and Saigo, 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

hh^UAS.cKa/Scer\GAL4^da.G32 is a suppressor | partially of Bolwig organ phenotype of Scer\GAL4^da.G32, ci^N:Zn.UAS

(Suzuki and Saigo, 2000)

hh^UAS.cKa/Scer\GAL4^da.G32 is a suppressor of Bolwig organ phenotype of ci^Ce-2

(Suzuki and Saigo, 2000)

hh^UAS.cKa/Scer\GAL4^da.G32 is a suppressor of Bolwig organ | germline clone phenotype of fu^mH63

(Suzuki and Saigo, 2000)

NOT Suppressor of

Statement

Reference

hh^UAS.cKa/Scer\GAL4^h-1J3 is a non-suppressor of Bolwig organ phenotype of eya^cli-IID

(Suzuki and Saigo, 2000)

hh^UAS.cKa/Scer\GAL4^da.G32 is a non-suppressor of Bolwig organ | germline clone phenotype of smo²

(Suzuki and Saigo, 2000)

hh^UAS.cKa/Scer\GAL4^h-1J3 is a non-suppressor of Bolwig organ phenotype of so³

(Suzuki and Saigo, 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Does not rescue the lack of Bolwig's organ neurons seen in so³ or eya^cli-IID embryos when expressed under the control of Scer\GAL4^h-1J3. The lack of Bolwig's organ neurons seen in fu^mH63 embryos is partially rescued by expression of hh^Scer\UAS.cKa under the control of Scer\GAL4^da.G32. Expression of hh^Scer\UAS.cKa under the control of Scer\GAL4^da.G32 considerably rescues the lack of Bolwig's organs seen in ci^Ce-2 embryos and in embryos expressing ci^{N:Zn.Scer\UAS} under the control of Scer\GAL4^da.G32.

(Suzuki and Saigo, 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

hh^UAS.cKa/Scer\GAL4^da.G32 partially rescues hh⁸

(Suzuki and Saigo, 2000)

hh^UAS.cKa/Scer\GAL4^h-1J3 partially rescues hh⁸

(Suzuki and Saigo, 2000)

Comments

The lack of Bolwig's organ neurons seen in hh⁸ embryos is partially rescued by hh^Scer\UAS.cKa expressed under the control of either Scer\GAL4^h-1J3 or Scer\GAL4^da.G32.

(Suzuki and Saigo, 2000)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

H. Kobayashi K. Saigo

(Suzuki and Saigo, 2000)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

hh^Scer\UAS.cKa

hh^UAS.cKa

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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