FlyBase Allele Report: Dmel\eya[G130]

General Information

Symbol

Dmel\eya^G130

Species

D. melanogaster

Name

FlyBase ID

FBal0103873

Feature type

allele

Associated gene

Dmel\eya

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

X ray

(Rebay et al., 2000)

ethyl methanesulfonate

(Rebay et al., 2000)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Rebay et al., 2000)

Phenotype Manifest In

Detailed Description

Statement

Reference

eya^G130/+ reduces the hatch rate of Abl¹/Abl² embryos from 90% to 20%.

(Xiong et al., 2009)

The penetrance of ectopic eye induction in eya^Scer\UAS.cHa; Scer\GAL4^dpp.blk1 flies is reduced from 98% (n=298) to 50% (n=313) by heterozygosity for eya^G130 (data from a single, 'strong' P{UAS-eya.H} insertion). The penetrance of ectopic eye induction in eya^S-A.Scer\UAS; Scer\GAL4^dpp.blk1 flies is reduced from 42% (n=306) to 20% (n=304) by heterozygosity for eya^G130 (data from a single, 'strong' P{UAS-eya^S-A} insertion). The penetrance of ectopic eye induction in eya^{SD.SE.Scer\UAS}; Scer\GAL4^dpp.blk1 flies is reduced from 92% (n=325) to 76% (n=322) by heterozygosity for eya^G130 (data from a single, 'strong' P{UAS-eya^SD.SE} insertion).

(Hsiao et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

eya^G130/eya[+] is an enhancer of partially lethal - majority live phenotype of Abl²/Abl¹

(Xiong et al., 2009)

Phenotype Manifest In

Enhancer of

Statement

Reference

eya^G130 is an enhancer of eye phenotype of Ras85D^N17.sev

(Rebay et al., 2000)

eya^G130 is an enhancer of eye phenotype of aop^S2382

(Rebay et al., 2000)

eya^G130 is an enhancer of eye phenotype of aop^ACT.sev

(Rebay et al., 2000)

eya^G130 is an enhancer of eye phenotype of aop^ACT.GMR

(Rebay et al., 2000)

eya^G130 is an enhancer of eye phenotype of Raf¹²

(Rebay et al., 2000)

NOT Enhancer of

Statement

Reference

eya^G130 is a non-enhancer of phenotype of Ras85D^V12.sev

(Rebay et al., 2000)

NOT Suppressor of

Statement

Reference

eya^G130 is a non-suppressor of phenotype of Ras85D^V12.sev

(Rebay et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Effect on aop^S2382 and Ras85D^N17.sev is mild. Effect on aop^ACT.GMR, aop^ACT.sev and phl¹² is moderate.

(Rebay et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

eya^A188

(Rebay et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

"X ray" was stated as tentative. "ethyl methanesulfonate" was stated as tentative.

(Rebay et al., 2000)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

cli^G130

eya^G130

(Xiong et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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