FB2024_03 , released June 25, 2024
Allele: Dmel\smg+t13.5
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General Information
Symbol
Dmel\smg+t13.5
Species
D. melanogaster
Name
FlyBase ID
FBal0102401
Feature type
allele
Associated gene
Dmel\smg
Associated Insertion(s)
Carried in Construct
P{smg+t13.5}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Dahanukar et al., 1999)
wild_type
(Dahanukar et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Dahanukar et al., 1999)
wild_type
(Dahanukar et al., 1999)
Mutagen
in vitro construct
(Dahanukar et al., 1999)
Progenitor genotype
Carried in construct
P{smg+t13.5}
Cytology
Description

A 13.5kb SalI fragment containing the smg coding region and 5kb of upstream promoter sequence.

(Dahanukar et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
smg
Encoded product / tool
smg
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3L:8,985,274..9,002,026 [-]
Linked to:
SalI-SalI restriction fragment
Comment:

Size of reported fragment differs from size of FlyBase computed fragment based on author statement: A 13.5kb SalI fragment containing the smg coding region and 5kb of upstream promoter sequence.

(Dahanukar et al., 1999)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos carrying six copies of smg+t13.5 are completely viable and show no segmentation defects.

      (Dahanukar et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      smg+t13.5 is a suppressor of embryo | anterior phenotype of BicDunspecified

      (Dahanukar et al., 1999)

      smg+t13.5 is a suppressor of embryonic head phenotype of BicDunspecified

      (Dahanukar et al., 1999)

      smg+t13.5 is a suppressor of embryonic thoracic segment phenotype of BicDunspecified

      (Dahanukar et al., 1999)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Embryos carrying nosΔBX in a nos- background and carrying two copies of smg+t13.5 develop 5 to 6 abdominal segments. Embryos carrying nosΔBX in a nos- background and carrying two copies of smg+t13.5 develop 2 abdominal segments. BicDunspecified embryos develop abdominal segments in the anterior of the embryo. This phenotype is suppressed by smg+t13.5; wild-type head and thoracic segments are specified normally and in many cases the embryos hatch.

      (Dahanukar et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      smg+t13.5 rescues smg1

      (Dahanukar et al., 1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      smg+t13.5
      Name Synonyms
      Secondary FlyBase IDs
        References (1)