FB2024_03 , released June 25, 2024
Allele: Dmel\fkhUAS.cRa
Open Close
General Information
Symbol
Dmel\fkhUAS.cRa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Rehorn
FlyBase ID
FBal0101424
Feature type
allele
Associated gene
Dmel\fkh
Associated Insertion(s)
Carried in Construct
P{UAS-fkh.R}
Also Known As
UAS-fkh
Key Links
Transgenic product class
cDNA
(Kusch and Reuter, 1999)
wild_type
(Kusch and Reuter, 1999)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Kusch and Reuter, 1999)
wild_type
(Kusch and Reuter, 1999)
Mutagen
in vitro construct
(Kusch and Reuter, 1999)
Progenitor genotype
Carried in construct
P{UAS-fkh.R}
Cytology
Description

fkh cDNA expression is governed by UAS regulatory sequences.

(Kusch and Reuter, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
fkh
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When expression is driven by Scer\GAL4twi.PGa the differentiation of the somatic mesoderm and the trunk visceral mesoderm is severely affected.

      (Kusch and Reuter, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      When expression of fkhScer\UAS.cRa and bynScer\UAS.cKa are driven together by Scer\GAL4twi.PGa there is a drastic increase in the number of anteriorly derived ectopic caudal visceral mesoderm cells form from the head mesoderm.

      (Kusch and Reuter, 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      fkhUAS.cRa/Scer\GAL4odd-106 rescues fkh6

      (Miguel-Aliaga et al., 2008)
      Comments

      Expression of fkhScer\UAS.cRa from embryonic stage 10 under the control of Scer\GAL4odd-106 rescues the apoptosis and pathfinding defects seen in fkh6 mutant anterior dMP2 neurons.

      (Miguel-Aliaga et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      K.P. Rehorn

      (Kusch and Reuter, 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      fkhScer\UAS.cRa
      fkhUAS.cRa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Rehorn
      (Kusch and Reuter, 1999)
      Secondary FlyBase IDs
        References (3)