FB2024_03 , released June 25, 2024
Allele: Dmel\stoutTA181
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General Information
Symbol
Dmel\stoutTA181
Species
D. melanogaster
Name
FlyBase ID
FBal0094322
Feature type
allele
Associated gene
stout
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

gain of function allele

Mutagen
Nature of the Allele
Allele class

gain of function allele

(Florence and McGinnis, 1998)
Mutagen
ethyl methanesulfonate
(Florence and McGinnis, 1998)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygotes and transheterozygotes with stout4 show defects surrounding the dorsal sac. Dorsal bridge is diffuse and occasionally unfused. Strands of sclerotic material are strung out from the anterior vertical plate and ventral side of the dorsal bridge. The H-piece lateral arm is bifurcated and the crossbar widened or broken. Mouth hooks are of normal length but are thin and the bases are often reduced. Third thoracic denticle belt is narrowed. This phenotype resembles that of EcR mutants. Heterozygous adults show thickened arista, arced wings and one or more kinked macrochaetae. When the mutant males carry two copies of the wild type locus, for example using Dp(1;3)sn13a1 or Dp(1;Y)ct+y+, males are sterile.

      (Florence and McGinnis, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      stoutTA181/stout[+] is an enhancer of partially lethal - majority die phenotype of Dfd13/Dfd3

      (Florence and McGinnis, 1998)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Allele may be neomorphic or antimorphic.

      (Florence and McGinnis, 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      stoutTA181
      Name Synonyms
      Secondary FlyBase IDs
        References (1)