FlyBase Allele Report: Dmel\dally[hs.PJ]

General Information

Symbol

Dmel\dally^hs.PJ

Species

D. melanogaster

Name

heat shock construct of Jackson

FlyBase ID

FBal0083021

Feature type

allele

Associated gene

Dmel\dally

Associated Insertion(s)

Carried in Construct

P{hs-dally.J}

Also Known As

hs-dally

Key Links

Transgenic product class

cDNA

(Jackson et al., 1997)

wild_type

(Jackson et al., 1997)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Jackson et al., 1997)

wild_type

(Jackson et al., 1997)

Mutagen

in vitro construct

(Jackson et al., 1997)

Progenitor genotype

Carried in construct

P{hs-dally.J}

Cytology

Description

dally cDNA is expressed under the control of a heat shock promoter.

(Jackson et al., 1997)

Allele components

Component

Use(s)

Regulatory region(s)

Hsp70

Encoded product / tool

dally

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell size | embryonic stage

(Tsuda et al., 1999)

Phenotype Manifest In

denticle

(Tsuda et al., 1999)

embryonic epidermis

(Tsuda et al., 1999)

nucleus | embryonic stage

(Tsuda et al., 1999)

Detailed Description

Statement

Reference

Ectopic expression of dally^hs.PJ after heat shock produces expansion of naked cuticle with a commensurate loss of denticles. They also have enlarged cells and enlarged condensed nuclei compared to wild type. When raised at 23.5^oC, dally^hs.PJ show no phenotype. Heat shock expression of dally^hs.PJ has no effect on the number of amnioserosa cells.

(Tsuda et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

dally^hs.PJ, hh^Mrt has visible phenotype

(Jackson et al., 1997)

dally^hs.PJ, hh^Mrt has visible | dominant phenotype

(Jackson et al., 1997)

Phenotype Manifest In

Enhancer of

Statement

Reference

dally^hs.PJ is an enhancer of phenotype of wg^PE2

(Moline et al., 2000)

fz2^UAS.cZa, dally^hs.PJ, Scer\GAL4^e22c is an enhancer of phenotype of wg^PE2

(Moline et al., 2000)

Suppressor of

Statement

Reference

dally^hs.PJ is a suppressor | partially of phenotype of wg^l-17/Df(2L)DE

(Moline et al., 2000)

dally^hs.PJ is a suppressor of embryonic head phenotype of wg^l-12

(Tsuda et al., 1999)

dally^hs.PJ is a suppressor of embryonic epidermis phenotype of wg^l-12

(Tsuda et al., 1999)

NOT Suppressor of

Statement

Reference

dally^hs.PJ is a non-suppressor of phenotype of wg^l-17

(Tsuda et al., 1999)

Other

Statement

Reference

dally^hs.PJ, hh^Mrt has wing | anterior phenotype

(Jackson et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

Ectopic expression of dally^hs.PJ can partially rescue wg^l-12 when raised at 23.5^oC (at this temperature wg^l-12 is a partial loss of function wg allele). Some head structures and patterning in the abdominal segment cuticle are restored. At 25^oC no rescue is observed. Heat shock expression of dally^hs.PJ cannot rescue wg^l-17.

(Tsuda et al., 1999)

Potentiates the hh^Mrt/+ phenotype, converting the wing overgrowth phenotype to mirror image wing duplications in hh^Mrt/+ ; dally^hs.PJ flies.

(Jackson et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

dally^hs.PJ rescues dally^ΔGAG

(Nakato et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dally^hs.PJ

Name Synonyms

heat shock construct of Jackson

(Jackson et al., 1997)

Secondary FlyBase IDs

References (4)

Report Sections

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