FB2024_03 , released June 25, 2024
Allele: Dmel\sli05248
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General Information
Symbol
Dmel\sli05248
Species
D. melanogaster
Name
FlyBase ID
FBal0064709
Feature type
allele
Associated gene
Dmel\sli
Associated Insertion(s)
P{PZ}sli05248
Carried in Construct
Also Known As
slit-lacZ
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{PZ}sli05248
Cytology
Description

Insertion between bases 10,985,837 and 10,985,838 on 2R, upstream of the 5' end of the sli transcript (which extends from bases 10,954,579 to 10,936,369) with the Ecol\lacZ coding region oriented away from the sli locus.

(Tayler et al., 2004)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      eye photoreceptor cell & axon (with slik04807b)

      (Tayler et al., 2004)

      lamina anlage (with slik04807b)

      (Tayler et al., 2004)
      Detailed Description
      Statement
      Reference

      slik04807b/sli05248 third instar larvae show defects in photoreceptor axon targeting, with gaps in the lamina and increased numbers of axons entering the medulla.

      (Tayler et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      (BDGP Project Members, 1994-1999)
      Comments
      Comments

      Complements: l(2)k02205k02205.

      (Misra, 2000.8.25)

      Complements: l(2)k02205k02205. Complements: l(2)k05713k05713. Complements: l(2)k08407k08407.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      l(2)05248
      (Misra, 2000.8.25, Spradling et al., 1999)
      l(2)0524805248
      (BDGP Project Members, 1994-1999)
      sli05248
      slil(2)k05248
      (Tayler et al., 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)