FB2024_03 , released June 25, 2024
Allele: Dmel\vkgk00236
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General Information
Symbol
Dmel\vkgk00236
Species
D. melanogaster
Name
FlyBase ID
FBal0063691
Feature type
allele
Associated gene
Dmel\vkg
Associated Insertion(s)
P{lacW}vkgk00236
Carried in Construct
Also Known As
l(2)k00236
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}vkgk00236
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The size distribution of regenerated adult wings in vkgk00236 heterozygous mutants that were subjected to ablation of imaginal wing disc tissue during the larval stage, is significantly shifted towards smaller wing size compared to similarly treated controls.

      (Khan et al., 2017)

      A small proportion of vkgk00236 mutant embryos display anterior Malpighian tubule path-finding defects, and the anterior pair of tubules to not extend into the anterior half of the embryo.

      (Bunt et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      vkg[+]/vkgk00236 is an enhancer of visible phenotype of Scer\GAL4sev.PU, Zzzz\CTGi480.UAS.cGa

      (Garcia-Lopez et al., 2008)

      vkg[+]/vkgk00236 is an enhancer of lethal | embryonic stage | recessive | partially phenotype of peb308

      (Wilk et al., 2004)
      Suppressor of
      Statement
      Reference

      vkg[+]/vkgk00236 is a suppressor of visible | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      vkg[+]/vkgk00236 is an enhancer of eye phenotype of Scer\GAL4sev.PU, Zzzz\CTGi480.UAS.cGa

      (Garcia-Lopez et al., 2008)
      Suppressor of
      Statement
      Reference

      vkg[+]/vkgk00236 is a suppressor of eye | heat sensitive phenotype of peb1

      (Wilk et al., 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      vkgk00236 dominantly enhances the rough eye phenotype caused by expression of Zzzz\CTGi480.Scer\UAS.cGa under the control of Scer\GAL4sev.PU.

      (Garcia-Lopez et al., 2008)
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)
      Comments
      Comments

      Complements: Cg25Ck00405. Complements: Cg25Ck03009. Complements: Cg25Ck03102. Complements: eIF-3p40k09003. Complements: eIF-3p40k09306. Complements: Cg25Ck09824. Complements: l(2)k10001k10001. Complements: l(2)k10127k10127. Complements: eIF-3p40k16615.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      l(2)k00236
      (Garcia-Lopez et al., 2008, Spradling et al., 1999)
      vkgK00236
      (Bunt et al., 2010)
      vkgk00236
      (Khan et al., 2017, Van De Bor et al., 2015, Koper et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)