A fourteen base-pair deletion (nucleotides 3706-3718 of the coding region) in the eighth exon in Asx. The deletion leads to a frame shift and an early stop codon.
A 14 bp deletion which removes nucleotides 3706-3718 of the coding region of the Asx 1670aa isoform. The deletion truncates the protein at aa 1235.
Homozygous Asxxen-72-3 mutant clones cause wing defects. The abnormalities include wing blisters, crumpling of the wing, bending or folding of the wing along the mutant clone, and dual-lobed wings. Patches of necrotic cells associated with Asxxen-72-3 mutant clones can be observed at low frequency.
Asxxen-72-3 mutant clone adult wings have patched of small cells containing more than one hair.
Homozygotes die as early larvae. Homozygous clones in the wing produce discrete, round blisters of variable size. These blisters can be located anywhere on the wing. Wing venation is normal. Homozygous embryos show no gross morphological abnormalities at hatching. Hatched larvae fail to grow.
Homozygous clones in the wing produce a blistered phenotype.
Asxxen-72-3 has visible | recessive | somatic clone phenotype, suppressible by Ubxunspecified
xen[+]/Asxxen-72-3 is a suppressor of viable phenotype of Ubxpbx-1/Ubx101
xen[+]/Asxxen-72-3 is a suppressor of viable phenotype of Ubxbx-3
Asxxen-72-3 has wing blade | somatic clone phenotype, suppressible by Ubxunspecified
The severity of wing phenotypes caused by homozygous Asxxen-72-3 mutant clones is reduced in a heterozygous Ubxunspecified mutant background. For example, no necrotic or dual-lobed wings are observed. In addition, the percentage of wing blisters or folded/bent wings is reduced and fewer flies have crumpled wings. In some cases, ripples are associated with visible clones containing small cells, whereas other ripples are not associated with the presence of smaller cells.
