In wild-type animals, exposure to 40Gy of γ rays induces a distinct pattern of apoptosis in the wing disc, focussed on the the wing pouch, but excluding the DV boundary region and prospective vein. In Dp^a4/Dp^a2 animals, the same irradiation treatment induces a different pattern of apoptosis, a smaller number of apoptotic cells are clustered in the center of the wing pouch, many in the D-V boundary region or prospective veins. This new pattern of apoptosis is consistent over time and follows the same kinetics as in wild-type. Marker analysis suggests that patterning of the wing disc (including vein and D-V boundary specification) is normal in these animals.

Disrupt G[[1]]-S transcription late in embryogenesis, DNA replication still occurs.

Hemizygotes exhibit kidney-shaped rough eyes, thin and short bristles on the thorax and head and severe abdominal abnormalities.

CycD², Dp^a4 has partially lethal | dominant phenotype

CycD¹, Dp^a4 has partially lethal | dominant phenotype

Dp^a4/Dp^a2 has wing disc | wandering third instar larval stage phenotype, suppressible by Df(3L)X14/+

Dp^a4/Dp^a2 has wing disc | wandering third instar larval stage phenotype, suppressible by Df(3L)XR38/+

Dp^a4/Dp^a2 has wing disc | wandering third instar larval stage phenotype, suppressible by Dark^CD4/Ark[+]