FlyBase Allele Report: Dmel\sc[me]

General Information

Symbol

Dmel\sc^me

Species

D. melanogaster

Name

FlyBase ID

FBal0059945

Feature type

allele

Associated gene

Dmel\sc

Associated Insertion(s)

Carried in Construct

Also Known As

sc^mes1

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Golovnin et al., 1999)

Progenitor genotype

Caused by aberration

In(1)y^2nssc^me

Cytology

Description

Inversion of the genomic region between the proximal defective P-element in y^+ns and a region in the sc gene. The inversion displaces sc enhancers away from the promoter.

(Golovnin et al., 1999)

Inversion breakpoint in sc.

(Gracheva et al., 1998)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Golovnin et al., 2002, Golovnin et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

More than 90% of flies lack the anterior orbital, humeral, presutural, anterior postalar and anterior supraalar bristles. More than 50% of flies lack the anterior notopleural, postvertical and ocellar bristles. Flies have 2 to 3 scutellar bristles.

(Golovnin et al., 2002)

(Golovnin et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

sc^me has visible phenotype, suppressible by su(Hw)^V/su(Hw)²

(Golovnin et al., 1999)

sc^me has visible phenotype, suppressible by mod(mdg4)^ul

(Golovnin et al., 1999)

sc^me has visible phenotype, suppressible by su(Hw)^NoAD

(Golovnin et al., 1999)

sc^me has visible phenotype, suppressible by su(Hw)^J

(Golovnin et al., 1999)

sc^me has visible phenotype, suppressible by su(Hw)^Δ100

(Golovnin et al., 1999)

sc^me has visible phenotype, suppressible by su(Hw)^Δ283

(Golovnin et al., 1999)

Phenotype Manifest In

Suppressed by

Statement

Reference

sc^me has anterior supraalar bristle phenotype, suppressible by su(Hw)^V/su(Hw)²

(Golovnin et al., 1999)

sc^me has scutellar bristle phenotype, suppressible by su(Hw)^V/su(Hw)²

(Golovnin et al., 1999)

sc^me has postocellar bristle phenotype, suppressible by mod(mdg4)^ul

(Golovnin et al., 1999)

sc^me has ocellar bristle phenotype, suppressible by mod(mdg4)^ul

(Golovnin et al., 1999)

sc^me has anterior postalar bristle phenotype, suppressible by mod(mdg4)^ul

(Golovnin et al., 1999)

sc^me has anterior supraalar bristle phenotype, suppressible by mod(mdg4)^ul

(Golovnin et al., 1999)

sc^me has scutellar bristle phenotype, suppressible by mod(mdg4)^ul

(Golovnin et al., 1999)

sc^me has ocellar bristle phenotype, suppressible by su(Hw)^NoAD

(Golovnin et al., 1999)

sc^me has presutural bristle phenotype, suppressible by su(Hw)^NoAD

(Golovnin et al., 1999)

sc^me has anterior postalar bristle phenotype, suppressible by su(Hw)^NoAD

(Golovnin et al., 1999)

sc^me has anterior supraalar bristle phenotype, suppressible by su(Hw)^NoAD

(Golovnin et al., 1999)

sc^me has scutellar bristle phenotype, suppressible by su(Hw)^NoAD

(Golovnin et al., 1999)

sc^me has anterior postalar bristle phenotype, suppressible by su(Hw)^Δ283

(Golovnin et al., 1999)

sc^me has anterior supraalar bristle phenotype, suppressible by su(Hw)^Δ283

(Golovnin et al., 1999)

sc^me has postocellar bristle phenotype, suppressible by su(Hw)^V/su(Hw)²

(Golovnin et al., 1999)

sc^me has ocellar bristle phenotype, suppressible by su(Hw)^V/su(Hw)²

(Golovnin et al., 1999)

sc^me has presutural bristle phenotype, suppressible by su(Hw)^V/su(Hw)²

(Golovnin et al., 1999)

sc^me has anterior postalar bristle phenotype, suppressible by su(Hw)^V/su(Hw)²

(Golovnin et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

The bristle phenotype is strongly suppressed by su(Hw)²/su(Hw)^V; only humeral, some anterior orbital and some anterior notopleural bristles are missing. The bristle phenotype is suppressed by su(Hw)^NoAD; only humeral, some anterior orbital, some anterior notopleural and some postvertical bristles are missing. The bristle phenotype is slightly suppressed by su(Hw)^Δ283; humeral and some anterior orbital, anterior notopleural, postvertical, ocellar, presutural and scutellar bristles are missing. The bristle phenotype is slightly suppressed by su(Hw)^J or su(Hw)^Δ100; humeral and some anterior orbital, anterior notopleural, postvertical, ocellar, presutural, anterior postalar, anterior supraalar and scutellar bristles are missing. The bristle phenotype is suppressed by mod(mdg4)^ul/mod(mdg4)^ul; only humeral, some anterior orbital, some anterior notopleural and some presutural bristles are missing.

(Golovnin et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

The effect of mutations in a number of loci involved in chromosome organisation on mutagenesis in the y^2ns sc^me double superunstable system has been analysed.

(Elagin et al., 1994)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

sc^me

sc^mes1

(Golovnin et al., 2002, Golovnin et al., 1999)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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